CT-based Abdominal Adipose Tissue Area Changes in Patients Undergoing Adrenalectomy Due to Cushing's Syndrome and Non-functioning Adenomas.

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
Elif Gündoğdu, Emre Emekli

Abstract

The majority of Cushing's syndrome (CS) cases constitute patients with functional adrenal adenomas. In adrenal CS, visceral adipose tissue (VAT) area, VAT/subcutaneous adipose tissue (SAT), and VAT/total adipose tissue (TAT) ratios are expected to decrease in response to adrenalectomy, although no change is expected in non-functioning adrenal adenomas (NFA). To evaluate the changes in VAT, SAT, TAT areas and VAT/SAT, VAT/TAT ratios using computed tomography (CT) in patients who underwent adrenalectomy due to adenomas. Preoperative and postoperative CT of 32 patients (16 with CS and 16 with NFA) were retrospectively evaluated. The VAT, SAT, TAT areas were obtained from CT at the level of L1-2 intervertebral disc space, and the VAT/SAT, VAT/TAT ratios were calculated. The postoperative parameter changes in both groups were evaluated compared to the preoperative values. The level of statistical significance was considered as p<0.05. The time interval between preoperative and postoperative CT measurements were 10.37 months (6-17) in CS and 9.75 months (7-15) in NFA groups (p=073). Preoperative CT indicated that the patients with CS had larger VAT and TAT areas (p=0.03, p=0.02) but SAT remained unchanged (p=0.08). However, postopera...Continue Reading

References

Jul 1, 1982·The American Journal of Clinical Nutrition·G A BorkanJ E Silbert
Apr 6, 1999·Radiology·T YoshizumiY Matsuzawa
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·Francesca Pecori GiraldiUNKNOWN Study Group on the Hypothalamo-Pituitary-Adrenal Axis of the Italian Society of Endocrinology
Sep 30, 2003·European Journal of Endocrinology·Luisa BarzonMarco Boscaro
Dec 4, 2003·European Journal of Endocrinology·A G RockallR H Reznek
Apr 13, 2005·Archives of Internal Medicine·Bret H GoodpasterAnne B Newman
Apr 3, 2012·International Journal of Urology : Official Journal of the Japanese Urological Association·Gavin Low, Kamal Sahi
Mar 13, 2013·European Journal of Internal Medicine·Serkan Yener
May 2, 2013·The Journal of Clinical Endocrinology and Metabolism·Miguel DebonoJohn Newell-Price
Jan 8, 2014·Endocrinology and Metabolism·Jongho KimIn Kyu Lee
Jul 1, 2012·International Journal of High Risk Behaviors & Addiction·Mansour ShahrakiNourallah Ramroudi
Jun 26, 2015·North American Journal of Medical Sciences·Hassan Al-ThaniAbdelHakem Tabeb
Apr 13, 2017·AJR. American Journal of Roentgenology·Cristina MosconiRenato Pasquali
May 17, 2019·Clinical Endocrinology·Sofie WenganderOskar Ragnarsson

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