CT characteristics and pathological implications of early stage (T1N0M0) lung adenocarcinoma with pure ground-glass opacity

European Radiology
Xin JinHai-yue Ju

Abstract

To analyze the CT characteristics and pathological classification of early lung adenocarcinoma (T1N0M0) with pure ground-glass opacity (pGGO). Ninety-four lesions with pGGO on CT in 88 patients with T1N0M0 lung adenocarcinoma were selected from January 2010 to December 2012. All lesions were confirmed by pathology. CT appearances were analyzed including lesion location, size, density, uniformity, shape, margin, tumour-lung interface, internal and surrounding malignant signs. Lesion size and density were compared using analysis of variance, lesion size also assessed using ROC curves. Gender of patients, lesion location and CT appearances were compared using χ²-test. There were no significant differences in gender, lesion location and density with histological invasiveness (P > 0.05). The ROC curve showed that the possibility of invasive lesion was 88.73% when diameter of lesion was more than 10.5 mm. There was a significant difference between lesion uniformity and histological invasiveness (P = 0.01). There were significant differences in margin, tumour-lung interface, air bronchogram with histological invasiveness ( P = 0.02,P = 0.00,P = 0.048). The correlation index of lesion size and uniformity was r = 0.45 (P = 0.00). The le...Continue Reading

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Citations

Sep 19, 2016·Diagnostic and Interventional Imaging·J G CohenG R Ferretti
Jun 4, 2017·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Benedikt H HeidingerAlexander A Bankier
Oct 19, 2017·AJR. American Journal of Roentgenology·Ming LiJagadeesan Jayender
Feb 9, 2018·Biomedical Engineering Online·Jing YangJiansong Ji
Apr 30, 2020·AJR. American Journal of Roentgenology·Zhi-Gang ChuFa-Jin Lv
Oct 9, 2020·Chest·Lea AzourWilliam H Moore
Jan 8, 2021·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Yining JiangZhiyong Li
Jun 1, 2021·Radiologic Clinics of North America·Lea AzourWilliam H Moore

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