CT colonography: same-day tagging regimen with iodixanol and reduced cathartic preparation

Abdominal Imaging
Emanuele NeriCarlo Bartolozzi

Abstract

The purpose of the study was to test the tagging performance and patient's acceptance of a reduced cathartic preparation, based on iodixanol and PEG, administered to patients 3 h before the exam. One hundred and thirty-two asymptomatic patients were enrolled. As colonic cleansing we used PEG macrogol 3350. For fluid tagging iodixanol was orally administered 3 h before the exam, in a total dose of 50 mL mixed with 34.8 g of PEG in 750 mL of water. Image's review showed 446 segments (56.4%) clean of feces and 346 segments (43.6%) with feces. Untagged fluid was observed in 74/706 (10.5%) segments; inhomogeneous tagging in 129/706 (16%); the average density of fluid was 1054.74 UH in the cecum-ascending colon and 905.14 UH in the descending-sigmoid colon; the average difference of density between right and left colonic segments was 149 UH, and it was statistically significant (P = 0.016). No side effects related to the consumption of Movicol were reported. Very few side effects related to the tagging solution were reported: mild nausea in 7 (0.05%) patients, mild diarrhea in 10 (0.07%). An average rank of 9 points (SD +/- 1) on a 10-point scale (10 = no discomfort, 0 = severe discomfort) resulted from the self-administered question...Continue Reading

References

Jan 1, 1978·Investigative Radiology·J G Johansen, S Kolmannskog
Sep 1, 1990·Investigative Radiology·K YamaguchiK Matsuura
Nov 3, 1998·AJR. American Journal of Roentgenology·B J SchmidtA G Bohorfoush
May 29, 2001·Radiology·M R CallstromK E Corcoran
Jun 8, 2001·Preventive Medicine·E R WeitzmanK V Goins
Feb 20, 2003·AJR. American Journal of Roentgenology·Branko M PlavsicValerie H Drnovsek
Dec 6, 2003·The New England Journal of Medicine·Perry J PickhardtWilliam R Schindler
Apr 15, 2004·JAMA : the Journal of the American Medical Association·Peter B CottonHarold Butler
Nov 3, 2004·Gastroenterology·Riccardo IannacconeRoberto Passariello
May 24, 2005·AJR. American Journal of Roentgenology·Philippe LefereBartel Van Holsbeeck
Jul 1, 2005·Radiology·Michael E ZalisUNKNOWN Working Group on Virtual Colonoscopy

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Citations

Aug 28, 2009·European Radiology·Delia CampanellaDaniele Regge
Sep 18, 2012·European Radiology·Emanuele NeriUNKNOWN ESGAR CT Colonography Working Group
Nov 26, 2009·AJR. American Journal of Roentgenology·Shmuel MahgereftehJacob Sosna
Apr 23, 2010·AJR. American Journal of Roentgenology·Aoife N KeelingMartina M Morrin
Feb 6, 2013·World Journal of Gastroenterology : WJG·Zhi-Yuan ChenJerome Z Liang
Mar 12, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Wenli CaiGordon J Harris
Jan 17, 2012·European Radiology·Carmen Zueco ZuecoManuela Fontanillo Fontanillo
Nov 26, 2010·Gastroenterology Clinics of North America·Don C Rockey
Jan 27, 2009·European Journal of Radiology·Daniele ReggeGabriele Chiara
May 16, 2013·IEEE Transactions on Bio-medical Engineering·Vincent F van RavesteijnFrans M Vos
Mar 15, 2013·European Journal of Radiology·Emanuele NeriCarlo Bartolozzi
Feb 17, 2018·Abdominal Radiology·Kevin J Chang, David H Kim
Feb 10, 2021·Abdominal Radiology·Alberto A Perez, Perry J Pickhardt

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