CT findings of acute radiation-induced pneumonitis in breast cancer.

The British Journal of Radiology
Wonguen JungKyubo Kim

Abstract

To evaluate the CT findings of acute radiation pneumonitis (RP) in breast cancer patients undergoing post-operative radiotherapy, and to analyze clinicodosimetric factors associated with acute RP. Between 2015 and 2017, 61 patients with breast cancer who underwent follow-up chest CT at 3 months after radiotherapy were analyzed. The degree of acute RP on CT was evaluated by the change of extent and scoring system (grade 0, no RP; Grade 1, ground-glass opacities (GGOs); Grade 2, GGOs and/or consolidations; Grade 3, clear focal consolidation; Grade 4, dense consolidation). The dosimetric parameters were calculated from the dose-volume histogram of RT. The acute RP on CT was scored as follows: Grade 0, in 37.7%, Grade 1 in 13.1%, Grade 2 in 44.3%, and Grade 3 in 4.9%. The median extent of RP in patients with Grades 1 to 3 was 6.2 ml (range, 0.2-95.9). There were no clinicodosimetric factors significantly associated with the presence of RP or its severity. One patient developed symptomatic RP. This study showed no correlation between acute RP and clinicodosimetric factors, and acute RP based on CT findings were much more common than symptomatic RP. CT findings of acute RP or extent of RP were not significantly related to clinicodosi...Continue Reading

References

Jul 3, 1996·Journal of the National Cancer Institute·S M BentzenJ Overgaard
Feb 9, 2006·Acta Oncologica·Ritva JärvenpääAntti Ojala
Mar 14, 2007·International Journal of Radiation Oncology, Biology, Physics·Zsuzsanna KahánLászló Thurzó
Oct 13, 2007·International Journal of Radiation Oncology, Biology, Physics·Marco KrengliAlessandro Carriero
Feb 14, 2009·International Journal of Radiation Oncology, Biology, Physics·X Allen LiUNKNOWN Radiation Therapy Oncology Group Multi-Institutional and Multiobserver Study
Sep 2, 2009·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ann YiBo Kyeong Seo
Feb 22, 2012·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Young-Taek OhHae-Jin Park
Mar 12, 2013·Clinical Radiology·M F K BenvenisteR F Munden
Jun 16, 2016·International Journal of Radiation Oncology, Biology, Physics·Sylvia VerbanckWalter Vincken
Oct 30, 2019·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Mahsa AbdemanafiIraj Abedi

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