CT-guided biopsy of lesions of the lung, liver, pancreas or of enlarged lymph nodes: value of additional fine needle aspiration (FNA) to core needle biopsy (CNB) in an offsite pathologist setting

Academic Radiology
Helmut SchoellnastGottfried J Schaffler

Abstract

To assess the value of additional fine needle aspiration (FNA) to core needle biopsy (CNB) in computed tomography-guided biopsy of lesions of the lung, liver, pancreas, or of enlarged lymph nodes in an offsite cytopathologist setting. This retrospective Health Insurance Portability and Accountability Act-compliant study was approved by the Institutional Review Board (IRB); informed consent (IC) was waived. Data of 377 patients who underwent computed tomography-guided FNA and CNB of lesions of the lung, liver, pancreas, or enlarged lymph nodes were enrolled. An onsite cytopathologist was not available. Sensitivity and specificity were calculated for FNA, CNB, and combined FNA/CNB. For the purpose of our study, positive diagnoses from CNB specimens or subsequent biopsy or surgical resection specimens or clinical follow-up data were considered as the standard of reference. CNB yielded a significantly higher sensitivity than FNA in all sites, except the pancreas, where the difference did not reach statistical significance. Additional FNA to CNB did not significantly increase the sensitivity. Specificity did not significantly differ between FNA, CNB, and combined FNA/CNB in all sites. Malignancies of 1.7% were detected only with FNA...Continue Reading

References

Feb 1, 1991·Australasian Radiology·B P LinR A Rose
Jul 1, 1995·AJR. American Journal of Roentgenology·L B Haramati
Jan 1, 1993·Acta Radiologica·T TikkakoskiM Apaja-Sarkkinen
Sep 1, 1997·AJR. American Journal of Roentgenology·P M BoiselleT C McLoud
Jul 6, 2000·AJR. American Journal of Roentgenology·H TsukadaT Souma
Jan 9, 2003·Gastrointestinal Endoscopy·Michael J LevyMaurits J Wiersema
Feb 20, 2003·AJR. American Journal of Roentgenology·Takuji YamagamiTsunehiko Nishimura
Jan 19, 2006·Cytopathology : Official Journal of the British Society for Clinical Cytology·J WittmannS P Pereira
Nov 26, 2008·Journal of Vascular and Interventional Radiology : JVIR·Mei-Hua TsouMing-Chih Chern

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Oct 23, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Young Keun SurYoung Bae Kim

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