CT-guided radiofrequency ablation: a potential complementary therapy for patients with unresectable primary lung cancer--a preliminary report of 33 patients

AJR. American Journal of Roentgenology
Giuseppe BelfioreRenato Rossi

Abstract

We report our preliminary evaluation of the effectiveness, safety, technical feasibility, and complications of palliative CT-guided radiofrequency ablation of unresectable primary pulmonary malignancies. Thirty-three patients (26 men and seven women; age range, 44-75 years; mean age, 66 years) with unresectable malignant lung neoplasms underwent 35 CT-guided tumor ablation sessions. Follow-up CT was performed 6 months (29 cases) and 1 year (10 cases) after treatment. In 19 patients, these findings were correlated with cytohistopathologic assessment obtained with CT-guided fine-needle aspiration biopsy or core biopsy at 6-month follow-up. Size and CT appearance of the treated lesions were correlated with cytohistologic features and clinical scores. Thirty-five technically successful radiofrequency ablation treatments were performed. The only complications in the periprocedural period were three cases of minor pneumothorax, five cases of sputum cruentum, and three asymptomatic pleural effusions. Contrast-enhanced CT performed at 6-month follow-up showed four cases of complete and 13 cases of partial lesion ablation, 11 cases of stabilized lesion size, and one case of increased lesion size. Contrast-enhanced CT performed at 1-year...Continue Reading

References

May 1, 1992·Journal of Vascular and Interventional Radiology : JVIR·J P McGahanP D Browning
Jul 1, 1993·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Y AnzaiR B Lufkin
Sep 1, 1995·Academic Radiology·S N GoldbergT C McLoud
Apr 8, 1998·AJR. American Journal of Roentgenology·S RossiL Buscarini
May 21, 1999·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·P J HollenC Cox
Jun 12, 1999·American Journal of Surgery·C H ScudamoreD A Owen
Jan 11, 2000·AJR. American Journal of Roentgenology·D E DupuyH Safran
Apr 12, 2000·International Journal of Radiation Oncology, Biology, Physics·J A LangendijkE F Wouters
Dec 9, 2000·Radiology·G S GazelleT Livraghi
Apr 17, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J A LangendijkE F Wouters
Jul 27, 2001·The Journal of Surgical Research·Y MiaoG Marchal
Sep 6, 2001·Journal of Vascular and Interventional Radiology : JVIR·S Nahum Goldberg, D E Dupuy
Oct 5, 2001·Journal of Vascular and Interventional Radiology : JVIR·D E Dupuy, S N Goldberg
Oct 5, 2001·The Journal of Urology·R J ZagoriaF M Torti
Mar 20, 2002·Cancer·Bradford J WoodStephen K Libutti
Sep 17, 2002·Journal of the American College of Surgeons·Tatsuya NishidaMasami Toyoshima
Oct 12, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Damian E DupuyThomas DiPetrillo
Apr 17, 2003·The Journal of Thoracic and Cardiovascular Surgery·Luis J HerreraJames D Luketich
Aug 2, 2003·Radiology·S Nahum GoldbergUNKNOWN International Working Group on Image-Guided Tumor Ablation
Aug 7, 2003·Journal of Vascular and Interventional Radiology : JVIR·Kamran AhrarKenneth C Wright
Aug 23, 2003·AJR. American Journal of Roentgenology·Sapna K JainThomas A DiPetrillo
Jan 15, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Matthew P GoetzJoseph Rubin

❮ Previous
Next ❯

Citations

Oct 19, 2007·Der Radiologe·R-T HoffmannM F Reiser
Nov 7, 2007·Cardiovascular and Interventional Radiology·Tomohisa OkumaYuichi Inoue
Jan 9, 2009·Cardiovascular and Interventional Radiology·Stephan ClasenPhilippe L Pereira
May 4, 2006·European Radiology·Christiane WeigelNorbert Hosten
Nov 17, 2007·European Radiology·Alice R Gillams, William R Lees
Jun 26, 2010·Current Treatment Options in Oncology·Millie DasNishita Kothary
Mar 12, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Karin Steinke
Mar 28, 2008·Annals of Surgical Oncology·Jacqui C ZhuDavid L Morris
Dec 23, 2008·AJR. American Journal of Roentgenology·Giuseppe BelfioreAntonio Rotondo
Jun 23, 2009·AJR. American Journal of Roentgenology·Nour-Eldin A Nour-EldinThomas J Vogl
Mar 30, 2007·Radiology·Caroline J SimonWilliam W Mayo-Smith
Oct 21, 2011·Radiology·Thomas J VoglNour-Eldin A Nour-Eldin
Jul 2, 2014·La Radiologia medica·Elena N PetreConstantinos T Sofocleous
Jul 13, 2012·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Fereidoun G AbtinRobert D Suh
Apr 14, 2015·Journal of Surgical Oncology·Maria P BelfioreGiuseppe Belfiore
Mar 4, 2014·Journal of Vascular and Interventional Radiology : JVIR·Nour-Eldin A Nour-EldinThomas J Vogl
Nov 19, 2013·Techniques in Vascular and Interventional Radiology·Yun Robert Sheu, Kelvin Hong
Dec 5, 2012·Chest·Jessica DoningtonUNKNOWN Thoracic Oncology Network of the American College of Chest Physicians and the Workforce on Evidence-Based Surgery of the Soc
Nov 20, 2008·Chest·Rika YoshimatsuTsunehiko Nishimura
Nov 24, 2011·Thoracic Surgery Clinics·Jessica S Donington, Justin D Blasberg
Aug 23, 2011·Journal of Vascular and Interventional Radiology : JVIR·Nour-Eldin Nour-EldinThomas J Vogl
Jul 6, 2011·Seminars in Roentgenology·Bradley B PuaStephen B Solomon
Mar 8, 2011·Surgical Oncology Clinics of North America·P David SonntagFred T Lee
Aug 7, 2010·Journal of Vascular and Interventional Radiology : JVIR·Bradley B PuaStephen B Solomon
May 19, 2010·Journal of Vascular and Interventional Radiology : JVIR·Sharon W KwanJonathan H Sunshine
Oct 24, 2006·Journal of Vascular and Interventional Radiology : JVIR·Takuji YamagamiTsunehiko Nishimura
Dec 23, 2006·Journal of Vascular and Interventional Radiology : JVIR·Takao HirakiSusumu Kanazawa
Jun 17, 2006·Journal of Vascular and Interventional Radiology : JVIR·Steven C RoseRalph B Vance
Feb 23, 2010·Clinics in Chest Medicine·Roberto F CasalGeorge A Eapen
Nov 27, 2009·Journal of Vascular and Interventional Radiology : JVIR·Filip BanovacKevin Cleary
Feb 28, 2009·Journal of Vascular and Interventional Radiology : JVIR·Steven C RoseUNKNOWN Technology Assessment Committee of the Society of Interventional Radiology
Apr 11, 2009·Seminars in Ultrasound, CT, and MR·Bradley B Pua, Stephen B Solomon
May 27, 2008·Clinical Lung Cancer·Sukhmani PaddaHeather Wakelee
Jul 30, 2008·Journal of Vascular and Interventional Radiology : JVIR·J Louis HinshawChristopher L Brace
Dec 12, 2007·Techniques in Vascular and Interventional Radiology·Ryan A McTaggart, Damian E Dupuy
Oct 4, 2007·Journal of Vascular and Interventional Radiology : JVIR·Takao HirakiSusumu Kanazawa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.