CT Perfusion in Acute Stroke Predicts Final Infarct Volume- Inter-observer Study

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
Jai Jai Shiva ShankarStephen Phillips

Abstract

Computed tomography perfusion (CTP) is increasingly being used in the setting of acute ischemic stroke (AIS). The aim of the current study was to compare the prognostic utility of, and inter-observer variation between, baseline appearances on non-contrast CT (using Alberta Stroke Program Early CT score(ASPECTS)) and on CTP for predicting final infarct volume. We also assessed impact of training on interpretation of these images. Retrospectively, plain head computed tomography (CT) and CTP images at presentation and CT or diffusion imaging on follow up of patients with AIS were analyzed. The lesion volume on different CTP parameters was then correlated with the final infarct volume. This analysis was done by a Neuroradiologist, a stroke Neurologist and a medical student. Kappa statistics and Intra-class correlation coefficients were used for agreement between readers. Pearson correlation coefficients were used. Thirty eight patients with AIS met all inclusion criteria. There was very good agreement among all readers for the CTP parameters. There was only fair agreement for ASPECT score. Correlation coefficient (r-square) between CTP parameters and final infarct volume showed that cerebral blood volume was the best parameter to p...Continue Reading

References

Apr 10, 2004·Stroke; a Journal of Cerebral Circulation·Shelagh B CouttsUNKNOWN VISION Study Group
Sep 2, 2004·Radiology·Stephan P KloskaWalter Heindel
Oct 30, 2012·Stroke; a Journal of Cerebral Circulation·Olga FinlaysonRichard I Aviv
Jan 1, 2013·AJNR. American Journal of Neuroradiology·J J S Shankar, R Vandorpe

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Citations

Jan 31, 2017·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Elizabeth H Y Du, Jai J S Shankar
Oct 2, 2017·Journal of Neurointerventional Surgery·Shlomi PeretzDavid Tanne
Nov 7, 2019·The Journal of Craniofacial Surgery·Luo YongjunZhou Junlin
Oct 18, 2019·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Sherry X HuStephen J Phillips
Jan 29, 2020·AJR. American Journal of Roentgenology·Jai Jai Shiva ShankarRobert Vandorpe
Oct 28, 2016·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Ruairi Meagher, Jai Jai Shiva Shankar
Feb 18, 2020·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Karim ViraniJai Jai Shiva Shankar
Jan 14, 2020·Stroke; a Journal of Cerebral Circulation·Salwa El-TawilUNKNOWN Study Collaborators
Feb 4, 2021·Neuroradiology·Giovanni FurlanisPaolo Manganotti

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