CT Scan-Guided Abrams' Needle Pleural Biopsy versus Ultrasound-Assisted Cutting Needle Pleural Biopsy for Diagnosis in Patients with Pleural Effusion: A Randomized, Controlled Trial

Respiration; International Review of Thoracic Diseases
Muzaffer MetintasSelma Metintas

Abstract

Image-guided pleural biopsies, both using ultrasound (US) or computed tomography (CT), are important in the diagnosis of pleural disease. However, no consensus exists regarding which biopsy needles are appropriate for specific procedures. In this randomized, prospective study, we aimed to compare CT scan-guided pleural biopsy using an Abrams' needle (CT-ANPB) with US-assisted pleural biopsy using a cutting needle (US-CNPB) with respect to both diagnostic yield and safety. Between February 2009 and April 2013, 150 patients with exudative pleural effusion who could not be diagnosed by cytological analysis were included in the study. The patients were randomized into either the US-CNPB group or the CT-ANPB group. The two groups were compared in terms of diagnostic sensitivity and complications. Of the 150 patients enrolled in this study, 45 were diagnosed with malignant mesothelioma, 46 were diagnosed with metastatic pleural disease, 18 were diagnosed with pleural tuberculosis, 34 were diagnosed with benign pleural disease, and 7 were lost to follow-up. In the US-CNPB group, the diagnostic sensitivity was 66.7%, compared with 82.4% in the CT-ANPB group; the difference between the two groups was statistically significant (p = 0.029...Continue Reading

Citations

Feb 1, 2017·Cardiovascular and Interventional Radiology·B T WelchG D Schmit
Apr 16, 2017·Thorax·John P CorcoranNajib M Rahman
Jun 19, 2019·Journal of Bronchology & Interventional Pulmonology·Muzaffer MetintasNajib Rahman
May 16, 2018·Internal Medicine Journal·Inés LosadaAntoni Payeras
Jun 20, 2019·Annals of the American Thoracic Society·Viren KaulOleg Epelbaum
Oct 17, 2017·Annual Review of Medicine·Ori Wald, David J Sugarbaker
Jan 22, 2021·Virchows Archiv : an International Journal of Pathology·Mary Beth BeasleySanja Dacic
Dec 10, 2020·Diagnostics·Anand SundaralingamNajib M Rahman
Sep 2, 2021·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Sanja Dacic

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