CT screening for lung cancer: prevalence and incidence of mediastinal masses

Radiology
Claudia I HenschkeNasser K Altorki

Abstract

To determine the frequency and natural course of mediastinal masses in asymptomatic people at high risk for lung cancer who were undergoing computed tomographic (CT) screening. Informed consent and institutional review board approval for this HIPAA-compliant study were obtained at each participating institution. All documented mediastinal masses among the 9263 baseline and 11 126 annual repeat screenings performed in the Early Lung Cancer Action Project (ELCAP) and its successor project, the New York ELCAP, were identified. Two radiologists confirmed all cases, identified the location and measured the diameter (average of length and width) of each mass, and reviewed all subsequent CT and clinical and surgical results. The prevalence and incidence of mediastinal masses were then determined. Of the 9263 individuals, 71 had a mediastinal mass seen at baseline screening (prevalence of 0.77%). Of the 71 masses, 41 were thymic, 16 were thyroidal, two were esophageal cancers, six were tracheal-esophageal diverticula, and six were other masses. Among the 11 126 annual repeat screenings, only one new mediastinal mass was identified (incidence of 0.01%). This suggests a long average duration for mediastinal masses in asymptomatic people....Continue Reading

References

Aug 1, 1985·AJR. American Journal of Roentgenology·I R FrancisB H Gross
Mar 1, 1982·AJR. American Journal of Roentgenology·G M GlazerA A Moss
Jan 1, 1982·Radiology·R L BaronR R Peterson
Jan 1, 1982·Radiology·R L BaronR G Levitt
Aug 1, 1980·Journal of Computer Assisted Tomography·R E BinderC T Sawin
Oct 1, 1994·Radiology·M L Rosado-de-ChristensonJ Galobardes
Oct 10, 1998·Clinical Radiology·K S Naik, R F Bury
Sep 22, 2001·AJR. American Journal of Roentgenology·Y W ChoiS R Lee
Oct 9, 2004·Clinical Imaging·Claudia I HenschkeOlli S Miettinen

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Citations

Jul 1, 2008·Radiological Physics and Technology·Shiho GomiNoriyuki Moriyama
Apr 2, 2008·Journal of Computer Assisted Tomography·Peter C A JacobsYolanda van der Graaf
Mar 31, 2010·Journal of Computer Assisted Tomography·Jin YamamuraUlrike Wedegärtner
Feb 21, 2013·Journal of Thoracic Imaging·Edith M Marom
Nov 18, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Rajbir K GillJin Jen
May 19, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Jos A StigtHarry J M Groen
Nov 15, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Brett W CarterEdith M Marom
Nov 15, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Brett W CarterEdith M Marom
Feb 22, 2011·Radiologic Clinics of North America·Jeffrey B Alpert, David P Naidich
Jun 3, 2008·Hematology/oncology Clinics of North America·Melissa L Rosado-de-ChristensonEdith M Marom
Jan 1, 2008·Clinical Imaging·Motoo NakagawaYuta Shibamoto
Nov 21, 2007·European Journal of Radiology·Noriyuki TomiyamaHironobu Nakamura
Feb 24, 2015·European Journal of Radiology Open·Tetsuro ArakiHiroto Hatabu
Jul 25, 2009·Journal of Magnetic Resonance Imaging : JMRI·Ahmed Abdel RazekOsama Hamza
Sep 1, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N GirardUNKNOWN ESMO Guidelines Committee
May 9, 2015·Magnetic Resonance Imaging Clinics of North America·Brett W CarterEdith M Marom
Nov 8, 2006·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Catherine ReadStephen Spiro
Jan 28, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Brett W CarterEdith M Marom
Oct 21, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Maria D MartinCristopher A Meyer
May 31, 2018·BMJ Case Reports·Robert Munashe MaweniSajid Chaudhry
Feb 1, 2019·Endocrinology, Diabetes & Metabolism Case Reports·C KamathL D Premawardhana
Aug 5, 2017·Topics in Magnetic Resonance Imaging : TMRI·Brett W CarterMarcelo F Benveniste
Feb 5, 2008·The Oncologist·Claudia I Henschke, David F Yankelevitz
Mar 20, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sang Hyup LeeJin Mo Goo
Apr 18, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Eui Jin HwangJeanne B Ackman
Aug 13, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jin Wang ParkYun Hyeon Kim
May 8, 2021·Journal of the American College of Radiology : JACR·UNKNOWN Expert Panel on Thoracic ImagingJeffrey P Kanne
Sep 24, 2021·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J L DicksonS M Janes
Oct 8, 2021·European Respiratory Review : an Official Journal of the European Respiratory Society·Maria-Rosa Ghigna, Vincent Thomas de Montpreville
Dec 11, 2021·Nuclear Medicine Communications·Haruto SugawaraMasahiko Kusumoto

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