CuBr-catalyzed efficient alkynylation of sp3 C-H bonds adjacent to a nitrogen atom

Journal of the American Chemical Society
Zhiping Li, Chao-Jun Li

Abstract

A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp3 C-H bond and sp C-H bond activations followed by C-C bond formation.

References

Dec 11, 2003·Journal of the American Chemical Society·Shun-Ichi MurahashiTakahiro Nakae
Apr 7, 2004·Proceedings of the National Academy of Sciences of the United States of America·Chunmei WeiChao-Jun Li
May 13, 2004·Journal of the American Chemical Society·Hiroyuki NakamuraJean-François Biellmann
May 21, 2004·Organic Letters·Huw M L Davies, Qihui Jin

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Citations

Jul 28, 2011·Journal of the American Chemical Society·Yusuke AnoNaoto Chatani
Feb 18, 2012·Journal of the American Chemical Society·Esther BoessMartin Klussmann
Aug 23, 2012·Journal of the American Chemical Society·Xuesong LiuChaozhong Li
Oct 29, 2013·Journal of the American Chemical Society·Qing-Yuan MengLi-Zhu Wu
Aug 10, 2011·The Journal of Organic Chemistry·Huangdi FengErik V Van der Eycken
Aug 10, 2012·The Journal of Organic Chemistry·Wei WeiXiaobing Wan
Oct 3, 2012·The Journal of Organic Chemistry·Qinqin Xia, Wanzhi Chen
Mar 30, 2013·The Journal of Organic Chemistry·Laura Ruiz EspeltTehshik P Yoon
Jul 20, 2011·Organic Letters·Shogo HashizumeMotomu Kanai
Jan 21, 2012·Organic Letters·Jonathan P Brand, Jérôme Waser
Feb 20, 2013·Organic Letters·Jayaraman DhineshkumarKandikere Ramaiah Prabhu
Apr 13, 2013·Organic Letters·Noriaki TakasuMotomu Kanai
Jun 14, 2013·Organic Letters·Umesh A KshirsagarDoron Pappo
Aug 31, 2013·Organic Letters·Sheng-rong GuoJian-nan Xiang
Sep 24, 2013·Organic Letters·Bin YangShang-Dong Yang
Jun 20, 2007·Chemical Society Reviews·Kevin R Campos
Jul 24, 2008·Chemical Society Reviews·Shun-Ichi Murahashi, Dazhi Zhang
Feb 14, 2009·Chemical Communications : Chem Comm·Youming ShenCan-Cheng Guo
Jun 9, 2009·Chemical Communications : Chem Comm·Jiri SroglDetlef Schröder
Jul 2, 2009·Chemical Communications : Chem Comm·Olivier Baslé, Chao-Jun Li
Apr 7, 2010·Chemical Communications : Chem Comm·Peng LiuChi-Ming Che
Oct 26, 2010·Chemical Communications : Chem Comm·Michael GhobrialMichael Schnürch
Nov 1, 2011·Chemical Communications : Chem Comm·Ri-Yuan TangJin-Heng Li

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