Cultural Adaptation and Validation of the Inflammatory Bowel Disease Disability Index in a Spanish Population and Its Association with Sociodemographic and Clinical Factors

International Journal of Environmental Research and Public Health
Rafael López-CortésCésar Hueso-Montoro

Abstract

Inflammatory bowel diseases generate disability. We aimed to adapt and validate the Inflammatory Bowel Disease Disability Index in a Spanish population and to analyze the sociodemographic and clinical factors associated with disability in patients with Crohn's disease and ulcerative colitis. Cultural adaptation and validation of psychometric properties in the index were done, along with an observational, cross-sectional, and analytical approach to determine associations with sociodemographic and clinical factors. Sociodemographic data, quality of life (using the Inflammatory Bowel Disease Questionnaire-32), and indicators of disease activity were collected, among others. A total of 170 subjects participated. The index showed high internal consistency, with a Cronbach's alpha of 0.869 and concurrent validity with the Inflammatory Bowel Disease Questionnaire-32 (r = 0.723, p < 0.001). The average score of the index was -3.91. Greater degrees of disability were found in women (mean = -6.77) than in men (mean = -1.25) (p = 0.018), in patients with Crohn's disease (mean = -5.94) rather than those with ulcerative colitis (mean = -0.94) (p = 0.028), and in patients in the moderately active disease phase (mean = -20.94) rather than tho...Continue Reading

References

Mar 8, 1980·Lancet·R F Harvey, J M Bradshaw
Oct 29, 1955·British Medical Journal·S C TRUELOVE, L J WITTS
May 6, 2004·Scandinavian Journal of Gastroenterology·T BernklevUNKNOWN IBSEN Study Group
Dec 15, 2010·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·F Casellas
Apr 16, 2011·The American Journal of Gastroenterology·Nicholas J TalleyUNKNOWN American College of Gastroenterology IBD Task Force
Jun 8, 2011·Gut·Laurent Peyrin-BirouletUNKNOWN International Programme to Develop New Indexes for Crohn's Disease (IPNIC) group
Aug 10, 2012·World Journal of Gastroenterology : WJG·Laurent Beaugerie, Harry Sokol
Feb 2, 2013·Salud pública de México·José María Ramada-RodillaGeorge L Delclós-Clanchet
Jul 11, 2013·World Journal of Gastroenterology : WJG·Cláudia Camila DiasFernando Magro
Oct 22, 2013·JAMA : the Journal of the American Medical Association·UNKNOWN World Medical Association
Sep 19, 2014·Current Gastroenterology Reports·Katharina BüschNick Bansback
Jan 9, 2015·Inflammatory Bowel Diseases·Mike van der HaveUNKNOWN Dutch Initiative on Crohn and Colitis
Jun 15, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Laurent Peyrin-BirouletBeth Rycroft
Dec 10, 2015·Gut·Corinne Gower-RousseauUNKNOWN International Programme to Develop New Indexes for Crohn's Disease (IPNIC) group
Jul 30, 2016·European Journal of Gastroenterology & Hepatology·João B SoaresRaquel Gonçalves
Nov 18, 2017·Therapeutic Advances in Gastroenterology·Patrick B AllenLaurent Peyrin-Biroulet

❮ Previous
Next ❯

Software Mentioned

R Commander
Statistical Package for the Social Sciences ( SPSS )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.