Cumulative conception and live birth rates after oocyte donation: implications regarding endometrial receptivity

Human Reproduction
R J PaulsonM V Sauer

Abstract

The purpose of the present study was to determine the cumulative likelihood of pregnancy success after repetitive cycles of oocyte donation and specifically to examine the influence of recipient age and diagnosis upon the cumulative likelihood of pregnancy in an effort to identify any potential subgroup of recipients who might have diminished endometrial receptivity. We retrospectively analysed the outcome of 418 consecutive embryo transfer cycles among 276 recipients of oocyte donation in our institution. We analysed clinical pregnancy and delivery rates in the recipients divided by age groups and diagnostic groups. For the purpose of life-table analysis, only cycles prior to and including the first cycle producing a successful pregnancy were included. Frozen-thawed embryo transfers were not included in the analysis. The overall clinical pregnancy rate was 36.2% (95% CI 31-41%) and the cumulative pregnancy rate after four cycles was 87.9%. The overall delivery rate was 29.3% (95% CI 25-33%) and the cumulative delivery rate after four cycles was 86.1%. There were no statistically significant differences in any of the rates attributable to recipient age or diagnosis. No decline in per cycle success was noted over consecutive cyc...Continue Reading

Associated Clinical Trials

Citations

Aug 4, 2007·Journal of Assisted Reproduction and Genetics·John Rinehart
Apr 9, 2008·Journal of Assisted Reproduction and Genetics·Eliezer GirshIlya Barr
Jul 5, 2013·Journal of Assisted Reproduction and Genetics·Daniel J KaserCatherine Racowsky
Feb 13, 2001·Fertility and Sterility·D E TourgemanR J Paulson
Aug 8, 1998·Fertility and Sterility·S D SpandorferZ Rosenwaks
Feb 13, 2001·Obstetrics and Gynecology·M S OpsahlJ D Schulman
Feb 24, 2001·Acta Obstetricia Et Gynecologica Scandinavica·V Söderström-AnttilaO Hovatta
Jun 15, 2010·Human Reproduction Update·M L P van der HoornS A Scherjon
Jan 26, 1999·Clinical Obstetrics and Gynecology·C Schmidt-Sarosi
Jan 26, 1999·Clinical Obstetrics and Gynecology·M A Cohen, M V Sauer
Feb 4, 2006·Clinical Obstetrics and Gynecology·Anne Z Steiner, Richard J Paulson
Dec 31, 2009·Reproductive Biology and Endocrinology : RB&E·Michal AmirEliezer Shalev
Mar 28, 2013·Journal of Human Reproductive Sciences·Pooja GuptaBhart Joshi
Oct 1, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Wendy van DorpIzaäk Schipper
Sep 2, 2011·Fertility and Sterility·Richard J Paulson
Dec 4, 2010·Reproductive Biomedicine Online·Malcolm FaddyKay Elder
Jul 29, 2010·Fertility and Sterility·Brian W WhitcombEric D Levens
Feb 14, 2006·Revue D'épidémiologie Et De Santé Publique·A Gougeon
Mar 12, 2008·Fertility and Sterility·Sérgio Reis SoaresCarlos Simón
Feb 13, 2007·Fertility and Sterility·Anne Z Steiner, Richard J Paulson
Aug 2, 2015·Journal of Reproductive Immunology·Lisa E E L O LashleyFrans H J Claas
Dec 3, 2003·Annals of the New York Academy of Sciences·Basil C Tarlatzis, Leonidas Zepiridis
Oct 23, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·A Vincent-RohfritschC Le Ray
Apr 17, 2001·American Journal of Obstetrics and Gynecology·R J PaulsonR Z Sokol
May 3, 2015·Fertility and Sterility·Mark V Sauer
Jun 12, 2012·Biochimica Et Biophysica Acta·Y E M KootN S Macklon
Jun 3, 2016·Endocrinology, Diabetes & Metabolism Case Reports·Ana Marina Moreira, Poli Mara Spritzer
Oct 17, 2016·Fertility and Sterility·Elodie GuesdonCamille Le Ray
Nov 3, 2016·The Medico-legal Journal·Shashank PooniyaTabin Millo
Jul 24, 2020·Human Fertility : Journal of the British Fertility Society·Jutharat AttawetElizabeth Sullivan
Oct 30, 2015·Current Opinion in Endocrinology, Diabetes, and Obesity·Meghan Hewlett, Shruthi Mahalingaiah
May 17, 2014·Arquivos brasileiros de endocrinologia e metabologia·Carmen Regina Leal de Assumpção
Jun 12, 2019·Journal of Assisted Reproduction and Genetics·Leigh A HumphriesDenny Sakkas
Oct 16, 2007·Arquivos brasileiros de endocrinologia e metabologia·Luiz Cesar VilodrePoli Mara Spritzer
Jul 31, 2021·Reproductive Biomedicine Online·Vanessa PataiaKamal K Ahuja

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.