Cumulative live birth rate following in vitro fertilization: study of 5,310 cycles

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Shai E ElizurJehoshua Dor

Abstract

Most previous studies that calculated cumulative delivery rates following in vitro fertilization (IVF) treatments were limited in the number of cycles and the implementation of intracytoplasmic sperm injection (ICSI). Therefore, we assessed the yield of high-order consecutive IVF treatments (up to 14 consecutive cycles) with and without ICSI. Data from IVF cycles performed in a single center were retrieved from a computerized database. A total of 5,310 cycles among 1,928 patients were evaluated and cumulative delivery rates until the first delivery were calculated using life-table analyses. There were 1,126 pregnancies resulting in 689 live births. Cumulative delivery rates reached 87% following 14 consecutive cycles. Cumulative delivery rates were higher following ICSI compared with cycles without (92.7% vs. 85.4%). In conclusion, each treatment cycle increased the cumulative delivery rate, resulting in a rate of 87% after 14 consecutive cycles. The introduction of ICSI resulted in the highest cumulative rates.

References

Oct 1, 1986·Fertility and Sterility·D S GuzickH W Jones
Jan 1, 1980·American Journal of Obstetrics and Gynecology·J DorD M Serr

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Citations

Feb 26, 2008·Journal of Assisted Reproduction and Genetics·Toshiki MatsuuraOsamu Kato
Jan 16, 2009·The New England Journal of Medicine·Beth A MaliziaAlan S Penzias
Apr 17, 2009·Human Reproduction·Michaël De BruckerHerman Tournaye
Jan 25, 2012·Human Reproduction·Marie WalschaertsPatrick Thonneau
Jul 16, 2010·Health Policy·Frida Simonstein
Nov 19, 2011·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·M BaumA Hourvitz
Apr 27, 2012·Journal of Health Services Research & Policy·Frida Simonstein, Michal Mashiach-Eizenberg
Jun 20, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Lars HogströmAnnsofie Adolfsson
Aug 29, 2013·Journal of Assisted Reproduction and Genetics·Michaël De BruckerMichel Camus
Mar 23, 2013·Journal of Assisted Reproduction and Genetics·Mehmet B CetinkayaPasquale Patrizio
Feb 15, 2011·Fertility and Sterility·Louise M StewartDavid B Preen
May 20, 2021·International Journal of Behavioral Medicine·Maayan AbramovYael Benyamini

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