CuNPs-magadiite/chitosan nanocomposite beads as advanced antibacterial agent: Synthetic path and characterization

International Journal of Biological Macromolecules
Adel MokhtarMohamed Sassi

Abstract

In this work, an inorganic-organic nanocomposite was prepared by combining copper exchanged-magadiite (Cu-magadiite) with chitosan. The synthesis was carried out by direct dispersion of the Cu-magadiite in the chitosan matrix. The mixture obtained is shaped into beads with an average diameter of about 1-1.2 mm. These beads were then contacted with a solution of NaBH4 in order to reduce loaded copper ions into copper nanoparticles species. The resulting nanocomposite (Cu-NPs-magadiite/chitosan) was characterized by XRD, FTIR, SEM, TG, UV-visible DR and EDX analysis. The results show that the magadiite was completely exfoliated confirming the formation of the organic-inorganic composite. Indeed, the encapsulation of magadiite was confirmed by the SEM images, which is presented as micron free aggregates included in the cavities of a continuous polysaccharide matrix. Otherwise, they confirm also the formation of CuNPs which are probably immobilized inside the magadiite-chitosan solid matrix. The antibacterial activity against E. coli and S. aureus was highlighted by the disc inhibition method and the minimum inhibitory concentration (MIC) was determined. The CuNPs-magadiite/chitosan nanocomposite showed a very efficient bactericida...Continue Reading

Citations

Feb 26, 2020·International Journal of Biological Macromolecules·Bai Qu, Yangchao Luo
Jul 8, 2020·International Journal of Biological Macromolecules·Ali H JawadZaher Mundher Yaseen
Nov 18, 2020·Mini Reviews in Medicinal Chemistry·Shilpi SrivastavaAtul Bhargava
Nov 5, 2020·Carbohydrate Polymers·Somaye RashkiHamed Mirzaei
Jan 4, 2022·ACS Applied Materials & Interfaces·Tiago G Dos SantosSimoni M P Meneghetti

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.