PMID: 8971305Dec 1, 1996Paper

Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers

Alimentary Pharmacology & Therapeutics
A PilottoG Valerio

Abstract

Specific data on anti-H. pylori treatments in elderly people are very scarce. The aim of the study was to evaluate in the elderly the efficacy of different anti-H. pylori therapies and the behaviour of serum anti-H. pylori antibodies, pepsinogen A and C, and PGA/PGC ratio induced by the anti-H. pylori treatment. One hundred and twenty-one dyspeptic patients aged > 60 years (mean age, 73 years; range, 61-89 years) with H. pylori-positive gastric ulcers (17 patients), duodenal ulcers (33 patients) or chronic gastritis (71 patients) were treated with one of the following anti-H. pylori treatments: (A) omeprazole 20 mg/day plus azithromycin 500 mg/day for 3 days; (B) omeprazole 20 mg/day plus azithromycin 500 mg/day for 3 days plus metronidazole 250 mg q.d.s. for 7 days; (C) omeprazole 40 mg/day plus azithromycin 500 mg/day for 3 days plus metronidazole 250 q.d.s. for 7 days; (D) omeprazole 20 mg/day plus clarithromycin 250 b.d. for 7 days; (E) omeprazole 20 mg/day plus clarithromycin 250 b.d. for 7 days plus metronidazole 250 q.d.s. for 7 days; and (F) omeprazole 40 mg/day plus clarithromycin 250 mg b.d. for 7 days plus metronidazole 250 mg q.d.s. for 7 days. At the baseline and 2 months after therapy, endoscopy and serum anti-H. ...Continue Reading

Citations

Aug 23, 2001·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·P Sherwood, R Spiller
Jan 6, 2001·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·A PilottoF Di Mario
Oct 13, 1998·Alimentary Pharmacology & Therapeutics·G A PipkinJ R Wood
Feb 7, 2002·Expert Opinion on Investigational Drugs·Joseph M BlondeauGlen T Hansen
Dec 19, 2009·Archives of Gerontology and Geriatrics·G RotoloM Barbagallo
Jun 23, 1999·Mayo Clinic Proceedings·S Alvarez-Elcoro, M J Enzler
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Dec 14, 2004·Best Practice & Research. Clinical Gastroenterology·Alberto Pilotto
Aug 11, 2019·Pharmacotherapy·Cynthia T NguyenJulius Li
Jun 18, 2003·European Journal of Gastroenterology & Hepatology·Aleksandra Sokic MilutinovicNeda Drndarevic
May 5, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·A PilottoG Valerio
Apr 4, 2002·Alimentary Pharmacology & Therapeutics·A Pilotto, P Malfertheiner
Jun 4, 1999·Journal of Gastroenterology and Hepatology·A PilottoG Valerio

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