Current applications of nanoparticles in infectious diseases

Journal of Controlled Release : Official Journal of the Controlled Release Society
Hinojal ZazoJosé M Lanao

Abstract

For decades infections have been treated easily with drugs. However, in the 21st century, they may become lethal again owing to the development of antimicrobial resistance. Pathogens can become resistant by means of different mechanisms, such as increasing the time they spend in the intracellular environment, where drugs are unable to reach therapeutic levels. Moreover, drugs are also subject to certain problems that decrease their efficacy. This requires the use of high doses, and frequent administrations must be implemented, causing adverse side effects or toxicity. The use of nanoparticle systems can help to overcome such problems and increase drug efficacy. Accordingly, there is considerable current interest in their use as antimicrobial agents against different pathogens like bacteria, virus, fungi or parasites, multidrug-resistant strains and biofilms; as targeting vectors towards specific tissues; as vaccines and as theranostic systems. This review begins with an overview of the different types and characteristics of nanoparticles used to deliver drugs to the target, followed by a review of current research and clinical trials addressing the use of nanoparticles within the field of infectious diseases.

References

Jun 1, 1978·Antimicrobial Agents and Chemotherapy·P F Bonventre, G Gregoriandis
Aug 1, 1998·Journal of Controlled Release : Official Journal of the Controlled Release Society·R LöbenbergJ Kreuter
Apr 17, 2003·Journal of the American Chemical Society·Alexander G TkachenkoDaniel L Feldheim
Jul 22, 2004·Bioconjugate Chemistry·Catherine M GoodmanVincent M Rotello
Aug 25, 2004·Clinics in Laboratory Medicine·Brenda Katz, Ken Waites
Nov 13, 2004·The Journal of Antimicrobial Chemotherapy·Franck FurnoHelen J Reid
Jan 29, 2005·Journal of Liposome Research·Hee-Jeong Kim, Malcolm N Jones
Apr 19, 2005·Molecular Pharmaceutics·Jayanth Panyam, Vinod Labhasetwar
Jul 19, 2005·Biomaterials·Fatiha ChellatL'Hocine Yahia
Nov 1, 2005·Tuberculosis·Rajesh PandeyG K Khuller
Apr 11, 2006·Journal of Drug Targeting·Vivek MishraSuresh P Vyas
Aug 29, 2006·Journal of Controlled Release : Official Journal of the Controlled Release Society·Ji Sun ParkYong Woo Cho
Oct 26, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Timothy J SpitzenbergerYuri Persidsky
Mar 27, 2007·Cell·Michael N Alekshun, Stuart B Levy
Apr 11, 2007·Bioorganic & Medicinal Chemistry Letters·Edward TurosDaniel V Lim
Jul 20, 2007·The Journal of Pharmacy and Pharmacology·Yashwant GuptaSanjay K Jain
Aug 9, 2007·Advanced Drug Delivery Reviews·Jaspreet K Vasir, Vinod Labhasetwar
Nov 28, 2007·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Jeffrey D KingsleyChristopher J Destache
Dec 8, 2007·Bioorganic & Medicinal Chemistry·Sampath C AbeylathDaniel V Lim
Dec 14, 2007·Journal of Controlled Release : Official Journal of the Controlled Release Society·Elsa BrionesJosé M Lanao
Jan 1, 2008·International Journal of Pharmaceutics·Misagh AlipourZacharias E Suntres
Mar 18, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Shunmugaperumal TamilvananAnnick Ludwig
Apr 9, 2008·Journal of Pharmaceutical Sciences·Naveed ShaikWilliam F Elmquist
Jun 17, 2008·Advanced Drug Delivery Reviews·Partha GhoshVincent M Rotello
Jun 25, 2008·Journal of Nanoscience and Nanotechnology·Priscyla D Marcato, Nelson Durán
Aug 19, 2008·Biomedical Materials·Rajeev Raghavan PillaiKenneth E Gonsalves
Jan 20, 2009·The Journal of Antimicrobial Chemotherapy·André C AmaralMaria Sueli S Felipe
Jan 24, 2009·Trends in Microbiology·Parham Sendi, Richard A Proctor
Feb 26, 2009·Journal of Drug Targeting·Suman RamtekeNarendra K Jain
Mar 6, 2009·Biomedical Materials·Priya BawaLisa C du Toit
Apr 7, 2009·The Journal of Antimicrobial Chemotherapy·Daoud Al-BadriyehDavid C M Kong
Jun 6, 2009·Cellular and Molecular Life Sciences : CMLS·Hervé Hillaireau, Patrick Couvreur
Aug 7, 2009·Drug Development and Industrial Pharmacy·Sumio ChonoKazuhiro Morimoto
Aug 12, 2009·Antimicrobial Agents and Chemotherapy·Mohamed N SeleemNammalwar Sriranganathan
Nov 17, 2009·Advanced Drug Delivery Reviews·Umesh Gupta, Narendra K Jain

❮ Previous
Next ❯

Citations

May 18, 2016·Experimental Biology and Medicine·Anna StejskalováBenjamin D Almquist
Feb 10, 2017·Nanomedicine·Seyed-Iman Roohani-Esfahani, Hala Zreiqat
Apr 7, 2017·ACS Applied Materials & Interfaces·Clément AnfraySamuel Valable
May 23, 2017·Therapeutic Delivery·Tânia Santos de AlmeidaCatarina Pinto Reis
Apr 13, 2018·Parasitology·Louise Donadello TessaroloAlice Maria Martins
Sep 26, 2017·Nature Reviews. Microbiology·Hyun KooLuanne Hall-Stoodley
Jul 4, 2018·Antimicrobial Agents and Chemotherapy·Ayaz AnwarNaveed Ahmed Khan
Jan 11, 2018·Parasites & Vectors·Ayaz AnwarRuqaiyyah Siddiqui
Sep 4, 2020·ChemPlusChem·Lili LiangGrzegorz Lisak
Jul 18, 2018·Frontiers in Microbiology·Pedro V BaptistaAlexandra R Fernandes
Dec 14, 2018·Nanoscale·Kenneth R SimsDanielle S W Benoit
Jan 27, 2019·Journal of Dental Research·Z RenH Koo
Oct 23, 2019·Frontiers in Pharmacology·Nan-Yao LeePo-Ren Hsueh
Dec 4, 2019·Nanomedicine·Joana MagalhãesSalette Reis
Aug 9, 2019·Scientific Reports·Christian Isalomboto Nkanga, Rui Werner Maçedo Krause
Oct 21, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yuanxiu HongJianzhong Du
Apr 19, 2017·FEMS Microbiology Reviews·Michal Natan, Ehud Banin
Jun 3, 2018·International Journal of Molecular Sciences·Clara I ColinoJosé M Lanao
May 3, 2019·PLoS Neglected Tropical Diseases·Juliana Souza Ribeiro CostaLaura Oliveira-Nascimento
Sep 23, 2018·Investigative Ophthalmology & Visual Science·Gabrielle GomartArnaud Sauer
Aug 7, 2019·International Journal of Molecular Sciences·María Vallet-RegíIsabel Izquierdo-Barba
Aug 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Arturo SánchezJahir Orozco
Jun 21, 2019·Current Pharmaceutical Design·Prasad MinakshiGaya Prasad
Apr 14, 2020·International Journal of Nanomedicine·Alexandru-Flaviu TăbăranLucian Mocan
May 14, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abuzer Alp YetisginOzlem Kutlu
Feb 14, 2017·Nano Convergence·Julius A Edson, Young Jik Kwon
Jan 3, 2019·American Journal of Therapeutics·Ariane de Jesus Sousa-BatistaRalph Santos-Oliveira

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

Related Papers

Future Microbiology
Natasha Leeson, Po-Ren Hsueh
American Journal of Clinical Dermatology
Hilde Ulvatne
Advanced Drug Delivery Reviews
Ching-Wen ChenPing-Shan Lai
Peptides
Jayaram Lakshmaiah Narayana, Jyh-Yih Chen
Recent Patents on Anti-infective Drug Discovery
Venetia Giannakaki, Spiros Miyakis
© 2022 Meta ULC. All rights reserved