Current approaches in the clinical management of pregnancy-associated breast cancer-pros and cons

The EPMA Journal
Pavol ZuborJan Danko

Abstract

Malignancies are one of the leading causes of mortality in women during their reproductive life. Treatment of gynecological malignant tumors during pregnancy is possible but not simple, since it creates a conflict between care of the mother and the fetus. BC is the most prevalent malignancy diagnosed in pregnancy, ranking up to 21% of all pregnancy-related malignancies. Due to its stets increasing prevalence, aggressive cancer subtype, and severe ethical and psychological aspects linked to the disease, experts raise an alarm for an acute necessity to improve the overall management of the PABC-the issue which has strongly motivated our current paper. Comprehensive research data and clinical experience accumulated in recent years have advanced our understanding of the disease complexity. PABC treatment must be individualized with an emphasis on optimal care of the mother, while observing standard treatment protocols with regard to safety of the fetus. Treatment protocols should be elaborated based on the individualized patient profile, bearing in mind the acute danger to the mother, maximizing the therapy efficacy and minimizing harmful effects to the fetus. Complex consulting on treatment options, their impacts on pregnancy and ...Continue Reading

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Citations

May 20, 2020·International Journal of Environmental Research and Public Health·Xiaosheng DongWenzhen Qiao
May 14, 2020·Breast Care·Barbara BuonomoFedro Alessandro Peccatori

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Methods Mentioned

BETA
biopsy
biopsies
X-ray
genotyping
dissection

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