PMID: 6105947Jan 1, 1980Paper

Current concept of diagnosis and therapy of acute pancreatitis (author's transl)

Deutsche Zeitschrift für Verdauungs- und Stoffwechselkrankheiten
P G Lankisch, H Koop

Abstract

Acute pancreatitis cannnot be diagnosed only by a single sign, symptom or laboratory determination, but on the basis of several clinical and biochemical findings. X-ray examinations and sonography are of limited diagnostic value in the initial phase. --Prognostic signs are helpful in the early evaluation of the course of the disease. --Intensive care in the initial stage is a decisive principle for adequate therapy. --The effect of hormonal and non-hormonal inhibition of pancreatic secretion or enzyme inhibition has not been proven sufficiently until now or has already been shown to be uneffective in controlled studies. --In contrast, albumin-, fluid- and electrolyte-replacement as well as pain relief and nasogastric suction in case of ileus are safe therapeutical procedures. --Besides shock renal and respiratory insufficiency are the most feared complications in acute pancreatitis and require early peritoneal dialysis and artificial ventilation including positive end expiratory pressure.

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