Current concepts and challenges in the radiologic assessment of brain tumors in children: part 2

Pediatric Radiology
Benita TamraziFelice D'Arco

Abstract

Assessing tumor response is a large part of everyday clinical work in neuroradiology. However in the setting of tumor treatment, distinguishing tumor progression from treatment-related changes is difficult on conventional MRI sequences. This is made even more challenging in children where mainstay advanced imaging techniques that are often used to decipher progression versus treatment-related changes have technical limitations. In this review, we highlight the challenges in pediatric neuro-oncologic tumor assessment with discussion of pseudophenomenon including pseudoresponse and pseudoprogression. Additionally, we discuss the advanced imaging techniques often employed in neuroradiology to distinguish between pseudophenomenon and true progressive disease.

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Citations

May 20, 2020·Pediatric Blood & Cancer·Inês AlvesFernando Carceller
Mar 6, 2021·AJNR. American Journal of Neuroradiology·C A P F AlvesF D'Arco
Sep 22, 2019·Journal of Neuroradiology. Journal De Neuroradiologie·Basile KerlerouxBaptiste Morel

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