Current concepts in joint pain in knee osteoarthritis

Der Schmerz
K MillsN Moloney

Abstract

Joint pain attributable to osteoarthritis (OA) is complex and influenced by a myriad of factors beyond local joint pathology. Current practice continues to predominantly adopt a biomedical approach to OA despite emerging evidence of the importance of a more holistic approach. This paper will summarise evidence for the presence of multidimensional pain profiles in knee joint pain and the presence of subgroups characterized by systemic features such as psychological distress, high comorbidity load or sensitisation of the nervous system. These factors have the potential to influence patient outcomes making them relevant for clinicians and highlighting the necessity of a broader multifactorial approach to assessment and treatment. This review describes the current state of the evidence for treatments of people with knee OA-related pain, including those receiving strong recommendations from current clinical guidelines, namely exercise, weight loss, self-management advice and pharmacological approaches. Other pain-modulating treatment options are emerging such as sleep and psychological interventions, pain education and multisensory retraining. The evidence and rationale for these newer therapeutic approaches is discussed. Finally, t...Continue Reading

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Citations

Feb 13, 2019·Der Schmerz·Marcus Schiltenwolf
Jul 10, 2019·Current Pain and Headache Reports·Vwaire OrhurhuAlaa Abd-Elsayed
Feb 27, 2020·Expert Opinion on Pharmacotherapy·Peihua CaoDavid J Hunter
Feb 27, 2020·Postgraduate Medicine·Francis Berenbaum, Chris Walker
May 23, 2020·Open Access Rheumatology : Research and Reviews·Marwa Yahia MahgoubWaleed Ahmed Hassan
Sep 16, 2020·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Su-Jin Cho

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