Current controversies in the management of patients with severe traumatic brain injury

ANZ Journal of Surgery
Alexios A AdamidesJeffrey V Rosenfeld

Abstract

Traumatic brain injury is a major cause of mortality and morbidity, particularly among young men. The efficacy and safety of most of the interventions used in the management of patients with traumatic brain injury remain unproven. Examples include the 'cerebral perfusion pressure-targeted' and 'volume-targeted' management strategies for optimizing cerebrovascular haemodynamics and specific interventions, such as hyperventilation, osmotherapy, cerebrospinal fluid drainage, barbiturates, decompressive craniectomy, therapeutic hypothermia, normobaric hyperoxia and hyperbaric oxygen therapy. A review of the literature was performed to examine the evidence base behind each intervention. There is no class I evidence to support the routine use of any of the therapies examined. Well-designed, large, randomized controlled trials are needed to determine therapies that are safe and effective from those that are ineffective or harmful.

References

Feb 1, 1978·Journal of Neurosurgery·L F MarshallH M Shapiro
Oct 1, 1977·Journal of Neurosurgery·J D MillerM J Rosner
Jan 1, 1992·Free Radical Biology & Medicine·D TorbatiW A Pryor
Mar 1, 1991·The American Journal of Emergency Medicine·D G MurphyR S Barreca
Feb 1, 1990·Journal of Neurosurgery·J L JaggiT W Langfitt
Mar 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·D I GrahamD R McLellan
Oct 1, 1988·Neurosurgery·D J GowerJ M McWhorter
Mar 1, 1988·American Journal of Surgery·G S Moss, S A Gould
Jul 1, 1987·Journal of Applied Physiology·T YusaB A Freeman
Dec 1, 1987·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R BustoM D Ginsberg
Jan 1, 1985·British Journal of Anaesthesia·H M Shapiro
Mar 1, 1985·Journal of Neurosurgery·J D WardR Keenan
Nov 1, 1984·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·M L SchwartzD F Andrews
Mar 1, 1984·The New England Journal of Medicine·C G MayhallR K Narayan
Oct 1, 1981·Journal of Neurosurgery·A M BurkeC Cerri
Apr 1, 1983·Neurosurgery·G L Rea, G L Rockswold
Dec 1, 1995·Journal of Neurosurgery·M J RosnerA H Johnson
Jan 1, 1994·Acta neurochirurgica·C G Paramore, D A Turner
Jan 1, 1993·Free Radical Research Communications·C K NarkowiczP W McCartney
Jan 1, 1993·Journal of Neurotrauma·G L CliftonS C Choi
Jan 1, 1996·The Journal of Surgical Research·R RabinoviciL F Neville
Apr 1, 1996·Journal of Neurosurgical Anesthesiology·M GemmaM Cenzato

❮ Previous
Next ❯

Citations

Sep 21, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·D Nast-KolbG Täger
Sep 21, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·C ProbstC Krettek
May 25, 2012·Current Neurology and Neuroscience Reports·Wendy L Wright
Apr 9, 2008·Neurocritical Care·Clemens M SchirmerAdel M Malek
Nov 8, 2012·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Guohua WangJun Chen
Aug 1, 2008·Chinese Journal of Traumatology = Zhonghua Chuang Shang Za Zhi·Gu LiWei-guo Liu
Mar 23, 2012·Journal of Neurotrauma·Joshua W GatsonJoseph P Minei
Apr 5, 2008·Current Opinion in Critical Care·Michael N Diringer
Oct 1, 2008·Neuromodulation : Journal of the International Neuromodulation Society·Jung-Tung LiuTzer-Bin Lin
Dec 8, 2011·Medical Gas Research·Wenwu LiuJohn H Zhang
Aug 21, 2013·Critical Care : the Official Journal of the Critical Care Forum·Rahul RajMarkus Skrifvars
Feb 3, 2009·Neuropsychiatric Disease and Treatment·Steven R FlanaganTeresa A Ashman
Apr 2, 2013·Journal of Neurosurgery·Joshua Wayne GatsonJane G Wigginton
Oct 10, 2013·Journal of Anaesthesiology, Clinical Pharmacology·Tumul ChowdhuryJayesh Daya
Aug 21, 2013·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Xiao-Er WeiWen-Bin Li
May 20, 2015·The Journal of Surgical Research·Hsiao-Yue WeeJinn-Rung Kuo
Sep 24, 2013·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Chih Hsiang ChuangJinn Rung Kuo
Jul 1, 2016·Journal of Neuroinflammation·Matthew ShermanJoshua W Gatson
Aug 16, 2016·Anesthesiology Clinics·Sayuri Jinadasa, M Dustin Boone
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Michael H BennettBenjamin Jonker
May 1, 2012·AACN Advanced Critical Care·Patricia A Blissitt
Sep 15, 2012·The Journal of Trauma and Acute Care Surgery·Tai-Jen ChuangJinn-Rung Kuo
Jul 12, 2017·Proceedings of the National Academy of Sciences of the United States of America·Austin ChouSusanna Rosi
Jan 25, 2013·Journal of Neurosurgical Anesthesiology·Shyamal R AsherMonica S Vavilala
May 17, 2017·Thorax·B R O'DriscollUNKNOWN BTS Emergency Oxygen Guideline Development Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.