Current Guidelines in the Management of Upper Gastrointestinal Subepithelial Tumors

Clinical Endoscopy
Jin Woong Cho, Korean ESD Study Group

Abstract

Subepithelial tumors are frequently found in asymptomatic patients in Japan and Korea where cancer screening tests routinely include endoscopy. Most lesions are asymptomatic and clinically insignificant. However, carcinoid tumors, lymphomas, glomus tumor and gastrointestinal stromal tumors (GISTs) are malignant or have the potential to become malignant. Inflammation due to parasitic infestation by Anisakis and poorly differentiated adenocarcinomas in the stomach rarely present as subepithelial lesions. In contrast to the frequency of gastric GIST in the gastrointestinal system, they are uncommon in the duodenum and very rare in the esophagus. The prognosis of patients with GISTs in the stomach is relatively good compared with GISTs in other organs. Along with the location of the tumor, its size and mitotic count are major factors that determine the malignant potential of GIST. Small (<2 cm) asymptomatic GISTs usually have benign clinical course. GIST is the most common subepithelial tumor to occur in the stomach. Although various methods are employed to diagnose GISTs, the risk of GIST metastasis cannot be accurately predicted before lesions are completely resected. Recently, new endoscopic diagnostic methods and treatment tech...Continue Reading

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Citations

Oct 18, 2016·Clinical Endoscopy·Eun Jeong Gong, Do Hoon Kim
Apr 17, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Ming-Yan CaiPing-Hong Zhou
May 8, 2019·AJR. American Journal of Roentgenology·Cheal Wung HuhByung-Wook Kim
May 1, 2019·Current Treatment Options in Gastroenterology·Anastassios C ManolakisYuto Shimamura
Apr 8, 2020·Molecular and Clinical Oncology·Prasit Mahawongkajit, Pakkavuth Chanswangphuvana
Nov 18, 2016·Clinical Endoscopy·Eun Jeong Gong, Kee Don Choi
Aug 24, 2017·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jeong Seok LeeHyeong Jin Kim
Jun 18, 2020·Cancer Management and Research·Fangxing Peng, Yao Liu
Aug 22, 2020·Curēus·Sheena MagoMicheal Tadros
Jul 18, 2019·Journal of General and Family Medicine·Zhehao Dai, Daiki Kobayashi
May 20, 2020·World Journal of Gastrointestinal Surgery·Lian-Song YeBing Hu
Sep 6, 2020·Current Opinion in Gastroenterology·Thomas R McCarty, Marvin Ryou
Nov 18, 2021·Clinical Endoscopy·Sun Moon KimUNKNOWN Research Group for Endoscopic Ultrasound of the Korean Society of Gastrointestinal Endoscopy

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Methods Mentioned

BETA
dissection
biopsy
surgical resection

Software Mentioned

ASGE

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