PMID: 7932033Apr 1, 1994Paper

Current methodologies for the study of pineal morphophysiology

Journal of Pineal Research
M G Welsh

Abstract

Light and electron microscopes, with or without the use of immunohistochemical techniques, have been the instruments of choice for study of the pineal complex even up to recent times. Other morphological technologies have become available during the past decade that, if applied to current questions concerning pineal morphophysiology, could add considerably to our understanding of this complex system. Those technologies discussed include confocal scanning laser microscopy (in conjunction with other techniques including immunohistochemistry and three-dimensional reconstruction), tissue culture methodologies, carbocyanine dyes (i.e., DiI), in situ hybridization, and application of microinjection methodologies. It is suggested that these technologies will be necessary for morphophysiologists to not only collaborate with molecular biologists and biochemists who study the pineal complex, but to corroborate the molecular and biochemical results of our colleagues.

References

Jul 11, 1977·Cell and Tissue Research·D FreundL Vollrath
Jul 10, 1992·Brain Research·J E García-MauriñoJ L Calvo
May 1, 1992·Microscopy Research and Technique·J A McNulty, L M Fox
Jan 1, 1991·Journal of Immunoassay·K TerazawaT Takatori
Sep 1, 1991·Journal of Chemical Neuroanatomy·P Wallén
Feb 1, 1991·The American Journal of Physiology·A K WilsonP De Lanerolle
May 1, 1990·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A J Elberger, M G Honig
Jan 1, 1990·The American Journal of Physiology·S BassnettD C Beebe
Jan 28, 1986·Biochemistry·H K KleinmanG R Martin
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M D SternE G Lakatta
Apr 6, 1984·Neuroscience Letters·T YamakuniY Takahashi

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Citations

Mar 1, 1997·Journal of Neuroscience Research·P RedeckerS Steinlechner
May 18, 2004·Anatomia, histologia, embryologia·G G OrtizR J Reiter

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