PMID: 7932033Apr 1, 1994Paper

Current methodologies for the study of pineal morphophysiology

Journal of Pineal Research
M G Welsh


Light and electron microscopes, with or without the use of immunohistochemical techniques, have been the instruments of choice for study of the pineal complex even up to recent times. Other morphological technologies have become available during the past decade that, if applied to current questions concerning pineal morphophysiology, could add considerably to our understanding of this complex system. Those technologies discussed include confocal scanning laser microscopy (in conjunction with other techniques including immunohistochemistry and three-dimensional reconstruction), tissue culture methodologies, carbocyanine dyes (i.e., DiI), in situ hybridization, and application of microinjection methodologies. It is suggested that these technologies will be necessary for morphophysiologists to not only collaborate with molecular biologists and biochemists who study the pineal complex, but to corroborate the molecular and biochemical results of our colleagues.


Jul 11, 1977·Cell and Tissue Research·D FreundL Vollrath
Jul 10, 1992·Brain Research·J E García-MauriñoJ L Calvo
May 1, 1992·Microscopy Research and Technique·J A McNulty, L M Fox
Jan 1, 1991·Journal of Immunoassay·K TerazawaT Takatori
Sep 1, 1991·Journal of Chemical Neuroanatomy·P Wallén
Feb 1, 1991·The American Journal of Physiology·A K WilsonP De Lanerolle
May 1, 1990·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A J Elberger, M G Honig
Jan 1, 1990·The American Journal of Physiology·S BassnettD C Beebe
Jan 28, 1986·Biochemistry·H K KleinmanG R Martin
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M D SternE G Lakatta
Apr 6, 1984·Neuroscience Letters·T YamakuniY Takahashi

❮ Previous
Next ❯


Mar 1, 1997·Journal of Neuroscience Research·P RedeckerS Steinlechner
May 18, 2004·Anatomia, histologia, embryologia·G G OrtizR J Reiter

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.