Current needs in pediatric pharmacoepidemiology

Pharmacoepidemiology and Drug Safety
Tamar LaskyRachel E Sobel

Abstract

We report on a needs assessment conducted by the International Society of Pharmacoepidemiology (ISPE) Pediatric Special Interest Group (SIG) to identify critical needs in pediatric pharmacoepidemiology and directions for future activities. A mixed methods survey using a structured interview was conducted in the SIG and ISPE membership to elicit information about current activities in pediatric pharmacoepidemiology and identify critical methodologic issues. The interviews were conducted in two phases over 2013 and 2014, beginning with interviews of SIG members and expanding to the wider ISPE membership. Members of the SIG conducted the interviews and summarized the responses. Twenty-nine ISPE members participated in the needs assessment The respondents reported working with a total of 59 distinct databases, with only eight databases used by more than one respondent. Seventeen respondents (57%) reported issues of limited sample sizes, noting that the problem intensifies when studying age sub-groups or specific genetic populations. Missing data elements were a problem in three main areas: lack of detailed medication information, inability to link to parental data, and lack of detailed information about age. Respondents reported th...Continue Reading

References

Feb 4, 2003·Pediatrics·Eric SchirmLolkje T W de Jong-van den Berg
Aug 21, 2003·JAMA : the Journal of the American Medical Association·Rosemary RobertsTerrie Crescenzi
Nov 4, 2008·Pharmacoepidemiology and Drug Safety·Antje NeubertUNKNOWN TEDDY Network of Excellence
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Mar 31, 2010·Pediatrics·Robert E ShaddyUNKNOWN Committee on Drugs and Committee on Pediatric Research
Mar 28, 2012·Anesthesia and Analgesia·Michael C SmithEugenie S Heitmiller
Apr 5, 2012·Clinical Pharmacology and Therapeutics·E Kimland, V Odlind
Oct 2, 2013·Pediatrics·Vilawan ChirdkiatgumchaiTanya E Froehlich
Feb 26, 2014·Pediatrics·Daniel A FrattarelliUNKNOWN American Academy of Pediatrics Committee on Drugs

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Citations

May 19, 2017·Drugs -- Real World Outcomes·Tamar Lasky
Feb 19, 2019·Thérapie·Florentia KaguelidouAntonio Clavenna

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