PMID: 25741549Jan 1, 2014Paper

Current pharmacotherapy of overactive bladder in neurological patients

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
P G ShvartsM A Kravchenko

Abstract

The literature data on the urgent neurological problem - overactive bladder (OAB) are summarized. The OAB prevalence, current conceptions on the physiology and pathophysiology of urination and pathogenetic mechanisms of OAB development are presented. Main groups of pharmacological agents used in OAB treatment are described. Special attention is drawn to rationale of using anticholinergic (antimuscarinic) drugs. The authors present the results of their own comparative analysis on the efficacy and tolerability of these drugs in treatment of patients with cerebral vascular diseases including the use of solifenacin succinate (VESIcare).

References

Mar 23, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·I Araki, S Kuno
Jun 3, 2000·Stroke; a Journal of Cerebral Circulation·P LanghorneG Murray

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