PMID: 11926177Apr 3, 2002Paper

Current practice of prophylactic anticoagulation in Guillain-Barré syndrome

Clinical Rehabilitation
T A Z K GaberJ R Jenner

Abstract

To document the incidence of venous thromboembolism in Guillain-Barré syndrome and current practice of anticoagulating these patients. Retrospective study. Acute neurology and rehabilitation wards in a teaching hospital. Seventy-three patients with Guillain-Barré syndrome admitted to Addenbrooke's Hospital from 1995 to 1999. Out of 73 patients, 50 were anticoagulated (68%) for 5-490 days with mean of 72 days. Anticoagulation was discontinued in 28 patients when they could walk independently and in six who were still wheelchair dependent. Five patients developed clinical deep venous thrombosis (DVT) (7%), three of them had pulmonary emboli. Venous thrombosis occurred in the first two months after onset in four patients. Two patients were not anticoagulated when they developed their DVT and the other three were on enoxaparin; one of these three had a pulmonary embolism and died. Despite prophylactic anticoagulants being used in the majority of patients admitted with major problems of mobility, 6% (3 out of 50) still developed clinically detected DVT and two developed pulmonary embolism. While this incidence is considerably lower than data reported before routine anticoagulation became a standard practice, these data reinforce the...Continue Reading

References

Mar 6, 1976·British Medical Journal·J Leese
Apr 3, 1976·British Medical Journal·C P BredinW H Morton
Apr 23, 1992·The New England Journal of Medicine·A H Ropper
Mar 1, 1994·Archives of Physical Medicine and Rehabilitation·D GreenM Tolotta

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Citations

Oct 3, 2002·Current Neurology and Neuroscience Reports·Deborah M Green
Aug 7, 2010·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Antonio Ramos-De la MedinaCarlos Muñoz-Joachim
Jun 21, 2013·Journal of the Peripheral Nervous System : JPNS·Simon Rinaldi
Jul 19, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·J B LillekerA M T Richardson
Feb 6, 2017·A & a Case Reports·Büşra TezcanAyşegül Özgök
Apr 1, 2011·The Neurohospitalist·Matthew Harms
Jun 16, 2010·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Alexandra LangJens D Rollnik
Apr 6, 2013·Korean journal of anesthesiology·Hyunbin KimSang-Hwan Do
Nov 24, 2006·Dimensions of Critical Care Nursing : DCCN·Stephanie B AtkinsonDonna Haynes
May 31, 2016·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·Yu V RyabinkinaP R Prokazova
Aug 7, 2019·Journal of the Peripheral Nervous System : JPNS·Ángela GómezSaúl Reyes
Jan 17, 2017·The American Journal of Case Reports·Nooshin SalehiRoger C Garrison
Aug 11, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Makoto NakajimaYukio Ando

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