Current PTCA practice and clinical outcomes in The Netherlands: the real world in the pre-drug-eluting stent era

European Heart Journal
Willem R P AgemaJ Wouter Jukema

Abstract

To document the practice of interventional cardiology and the clinical restenosis rate, as well as the risk factors for clinical restenosis in an unselected population of patients in daily practice and to provide a perspective for the need of new devices such as drug-eluting stents. A total of 3177 consecutive patients, who underwent successful percutaneous transluminal coronary angioplasty (PTCA) in the Netherlands, were included. Patients with acute myocardial infarction were excluded. The pre-defined end-point of clinical restenosis was defined as cardiac death, myocardial infarction and revascularisation of the target vessel. Follow-up (9.6 months, IQR 3.9) was complete in 3146 (99.3%) patients with a mean age of 62.1+/-10.7 years. Of them 896 (28.5%) were female, 459 (14.6%) had diabetes and 1459 (46.4%) had multi-vessel disease. Most patients (2105, 66.9%) were treated for stable angina. Of all patients, 819 (26.0%) were treated for multiple lesions, 2340 (74.4%) underwent stenting and 820 (26.1%) received glycoprotein IIb/IIIa inhibitors. All stented patients received life-long aspirin and ticlopidin/clopidogrel during at least 1 month after the procedure. Target vessel revascularisation during follow-up by either corona...Continue Reading

Citations

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Jul 27, 2011·Stroke Research and Treatment·Stella TrompetJ Wouter Jukema
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Mar 3, 2010·European Journal of Clinical Investigation·Panagiota GeorgiadouDimitrios T Kremastinos
Sep 20, 2005·Journal of the American College of Cardiology·Pascalle S MonraatsJ Wouter Jukema
Nov 21, 2015·PloS One·Tonia C RothuizenJoris I Rotmans
Sep 14, 2011·Nature Reviews. Cardiology·J Wouter JukemaPaul H A Quax
Oct 19, 2005·Circulation·Pascalle S MonraatsJ Wouter Jukema
Apr 6, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Jeffrey J W VerschurenJoris I Rotmans
Mar 27, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Chihiro HosodaAkito Tanoue
Dec 2, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Pascalle S MonraatsJ Wouter Jukema

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