Current readings: the most influential and recent studies regarding resection of lung cancer in m1a disease

Seminars in Thoracic and Cardiovascular Surgery
P MordantM Riquet

Abstract

M1A disease is a recent concept appearing in the 7th TNM classification of lung cancer. M1A encompasses two different entities, malignant pleural or pericardial effusions and separate tumor nodules in the contralateral lung, who constitute very different diseases, with very different management and prognoses. On one hand, patients with pleural dissemination have extremely poor survival, with median and 5-year survivals of 4 months and 3.1%, respectively. Only selected patients whose limited pleural extension has been diagnosed at the time of thoracotomy and completely resected, may experience prolonged survival. On the other hand, recent progress in molecular biology still failed to establish whether a contralateral lesion is a second primary or a metastasis. These contralateral lesions are now gathered as multiple lung cancers in the surgical literature, and misleadingly classified as M1A disease in the TNM classification. Patients with contralateral nodules may experience prolonged survival after the surgical treatment of both localizations. Changing the staging by establishing the diagnosis of metastasis is probably an important issue warranting further biologic research, but according to current results this diagnosis must ...Continue Reading

References

Apr 20, 2001·The Annals of Thoracic Surgery·D Manac'hC Danel
Jul 4, 2007·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Ramón Rami-PortaUNKNOWN Participating Institutions
Sep 1, 2007·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Pieter E PostmusUNKNOWN Participating Institutions
Mar 5, 2008·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Sai-Hong Ignatius Ou, Jason A Zell
Aug 30, 2008·The Annals of Thoracic Surgery·Marc RiquetEugeniu Banu
Nov 27, 2009·The Journal of Thoracic and Cardiovascular Surgery·Eric LimUNKNOWN International Pleural Lavage Cytology Collaborators
Jan 23, 2010·Interactive Cardiovascular and Thoracic Surgery·Michitaka KimuraShigeki Taniguchi
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Apr 26, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Pierre MordantMarc Riquet
Nov 9, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·T TanvetyanonL A Robinson

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Citations

Sep 1, 2014·The Journal of Thoracic and Cardiovascular Surgery·Kotaro KameyamaUNKNOWN Japanese Joint Committee of Lung Cancer Registry
Aug 28, 2017·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Elizabeth A DavidRobert J Canter

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