Current state of the art imaging approaches for colorectal liver metastasis

Hepatobiliary Surgery and Nutrition
Bita HazhirkarzarIhab R Kamel

Abstract

One of the most common cancers worldwide, colorectal cancer (CRC) has been associated with significant morbidity and mortality and therefore represents an enormous burden to the health care system. Recent advances in CRC treatments have provided patients with primary and metastatic CRC a better long-term prognosis. The presence of synchronous or metachronous metastasis has been associated, however, with worse survival. The most common site of metastatic disease is the liver. A variety of treatment modalities aimed at targeting colorectal liver metastases (CRLM) has been demonstrated to improve the prognosis of these patients. Loco-regional approaches such as surgical resection and tumor ablation (operative and percutaneous) can provide patients with a chance at long-term disease control and even cure in select populations. Patient selection is important in defining the most suitable treatment option for CRLM in order to provide the best possible survival benefit while avoiding unnecessary interventions and adverse events. Medical imaging plays a crucial role in evaluating the characteristics of CRLMs and disease resectability. Size of tumors, proximity to adjacent anatomical structures, and volume of the unaffected liver are am...Continue Reading

Citations

Sep 26, 2020·Frontiers in Bioengineering and Biotechnology·Hermann B FrieboesBiana Godin
Aug 9, 2021·Annals of Surgical Oncology·Brett S WalkerMelissa H Wong

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