Current status and perspective of antiangiogenic therapy for cancer: hepatocellular carcinoma.

International Journal of Clinical Oncology
Shinji Tanaka, Shigeki Arii

Abstract

Hepatocellular carcinoma (HCC) is well known as a typical angiogenic tumor, especially in the moderately to poorly differentiated type. Such clinicopathological characteristics are not only useful for imaging diagnosis but are also applicable to the treatment of HCC. In addition, recent molecular studies have revealed that angiogenesis is closely related to hepatocarcinogenesis. In this review, the molecular mechanism of HCC angiogenesis and the antiangiogenic prevention of HCC are reviewed to introduce the latest trends in antiangiogenic treatment of cancers, including HCC.

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Citations

Apr 28, 2011·Naunyn-Schmiedeberg's Archives of Pharmacology·Massimo Dal MontePaola Bagnoli
Feb 26, 2011·Journal of Gastroenterology·Shinji Tanaka, Shigeki Arii
May 28, 2010·International Journal of Clinical Oncology·Shinji Tanaka, Shigeki Arii
Jul 2, 2008·Digestive Diseases and Sciences·Geng-Wen HuangXiang Ding
Apr 9, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jenny C HoSheung Tat Fan
Jul 29, 2008·Cancer Letters·Su Cheol ParkHyo-Suk Lee
Nov 15, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Kota SatoShigeki Arii
Nov 29, 2008·Cancer Science·Shinji Tanaka, Shigeki Arii
May 11, 2015·GE Portuguese Journal of Gastroenterology·Pedro Boal Carvalho, Eduardo Pereira
Aug 1, 2012·Seminars in Oncology·Shinji Tanaka, Shigeki Arii

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