Current status of esophageal cancer treatment

Chinese Journal of Cancer Research = Chung-kuo Yen Cheng Yen Chiu
Tania Triantafyllou, Bas P L Wijnhoven

Abstract

Esophageal cancer (EC) remains one of the most common and aggressive diseases worldwide. This review discusses some debates in the modern management of the disease. Endoscopic procedures for early cancer (T1a-b) are now embedded in routine care and the challenge will be to more accurately select patients for endoscopic resection with or without adjuvant therapy. Perioperative multimodal therapies are associated with improved survival compared to surgery alone for locally advanced esophageal cancer. However, there is no global consensus on the optimal regimen. Furthermore, histological subtype (adenocarcinomavs. squamous cell cancer) plays a role in the choice for treatment. New studies are underway to resolve some issues. The extent of the lymphadenectomy during esophagectomy remains controversial especially after neoadjuvant chemoradiation. The ideal operation balances between limiting surgical trauma and optimizing survival. Minimally invasive esophagectomy and enhanced recovery pathways are associated with decreased morbidity and faster recovery albeit there is no consensus yet what approach should be used. Finally, immune checkpoint inhibitors present promising preliminary results in the novel treatment of advanced or metas...Continue Reading

Citations

Dec 4, 2020·International Journal of Cancer. Journal International Du Cancer·Chung S Yang, Xiaoxin Luke Chen

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection
imaging techniques
dissection
dissections

Software Mentioned

ROBOT

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Annals of the New York Academy of Sciences
Alicia S BorggreveLucas Goense
Annals of Oncology : Official Journal of the European Society for Medical Oncology
Marek KollarJan Martinek
Journal of Gastroenterology and Hepatology
Susan Gan, David I Watson
© 2021 Meta ULC. All rights reserved