Current status of immunosuppressive agents for solid organ transplantation in children

Pediatric Transplantation
Tracy CoelhoAnil Dhawan

Abstract

Immunosuppression after organ transplantation is complex and ever evolving. Over the past two decades, newer immunosuppressive agents have been introduced with an aim to provide better patient and graft survival. Improved therapeutic strategies have been developed offering the option to use combinations of drugs with non-overlapping toxicities. There are, however, only a few clinical studies with robust data to rationalize the use of these agents in children. This review will discuss the newer immunosuppressive agents used for solid organ transplant, their current status in post-transplant management and prevention of allograft rejection.

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Aug 9, 2013·Paediatric Drugs·D ThangarajahA Dhawan
Sep 7, 2013·Advances in Pediatrics·Jonathan P Roach, Frederick M Karrer
Jun 9, 2012·Pediatric Transplantation·Paula Alejandra Coccia, Jorge Roberto Ferraris
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Aug 2, 2019·Current Opinion in Pediatrics·Sara HassanAmal Aqul
May 16, 2019·Current Opinion in Organ Transplantation·Tobias M Benoit, Christian Benden
Jul 3, 2019·International Journal of Molecular Sciences·Wei ZhangSatohiro Masuda

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