Current status of the gyro centrifugal blood pump--development of the permanently implantable centrifugal blood pump as a biventricular assist device (NEDO project)

Artificial Organs
Y Nosé, Kojiro Furukawa

Abstract

The New Energy and Industrial Technology Development Organization (NEDO) project was started in 1995. The goal is the development of a multipurpose, totally implantable biventricular assist device (BVAD) that can be used for any patient who suffers from severe heart failure. Our C1E3 (two-week pump) centrifugal pump, called the Gyro pump, has three design characteristics: a magnetic coupling and double pivot bearing system, an eccentric inlet port, and secondary vanes on the bottom of the impeller. The pump was miniaturized. The C1E3 evolved into the NEDO PI-601, a totally implantable centrifugal pump for BVAD. The current NEDO PI-710 pump (five-year pump) system includes a centrifugal pump with pivot bearings, a hydraulically-levitated impeller, an rpm-controlled miniaturized actuator (all-in-one actuator plus controller), an emergency clamp on the left outflow, and a Frank-Starling-type flow control. The final mass production model is now finalized, and the final animal study and two-year endurance studies are ongoing.

References

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Citations

Jun 19, 2007·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Yusuke AbeKou Imachi
Aug 29, 2012·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Yusuke AbeKou Imachi
Jul 9, 2011·Annals of Biomedical Engineering·Shaun D GregoryJohn F Fraser
Dec 13, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kiyotaka FukamachiLeonard A R Golding
Dec 13, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yoshio OotakiKiyotaka Fukamachi
Feb 24, 2005·Artificial Organs·Paul S Malchesky
Jan 18, 2006·Artificial Organs·Takashi YamaneYukihiko Nosé
May 2, 2007·Artificial Organs·Ryo KosakaTakashi Yamane
Jul 17, 2010·Artificial Organs·Nicholas Richard GaddumMark John Pearcy
Aug 14, 2012·Artificial Organs·Shaun David GregoryDaniel Timms
Sep 26, 2015·Journal of Cardiac Surgery·Carson S FoxAmy L Throckmorton
Jul 11, 2006·Cell Transplantation·Harvey S BorovetzR E Shaddy
Jun 9, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Daisuke OgawaYukihiko Nosé
Jan 22, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Diyar SaeedKiyotaka Fukamachi
Oct 9, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shiori Oshima, Yoshiyuki Sankai
Jan 28, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kojiro FurukawaYukihiko Nosi

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