PMID: 8598504Jan 1, 1996Paper

Current use of thiazide diuretics and prevention of femur fractures

Journal of Clinical Epidemiology
Ron M C HeringsA Stergachis

Abstract

A case control study of a defined population from The Netherlands was performed to evaluate the risk of femur fractures associated with the use of thiazide diuretics. Included were 386 patients hospitalized for femur fractures between 1986 and 1990 who were residents and 45 years of age and older. Per case, one age-, sex-, pharmacy-, and general practitioner-matched control was chosen from the general population. Drug use was ascertained from computerized pharmacy records. The adjusted odds ratio of current use of thiazide diuretics was 0.5 (95% confidence interval, 0.3-0.9). The protective effect of thiazide diuretics was greatest for use of 1 year or longer at relatively high doses of thiazides (odds ratio, 0.3; 95% confidence interval, 0.1-0.9). We also found that patients who discontinued thiazide use longer than 2 months were not protected against femur fractures. These results support the hypothesis that use of thiazide diuretics protects against femur fractures.

References

Jan 1, 1978·Age and Ageing·L Wollner
Jun 1, 1992·Journal of Clinical Epidemiology·R A DeyoM A Ciol
Jul 1, 1991·Annals of Internal Medicine·F E HeidrichK M Gross
Jul 1, 1991·Annals of Internal Medicine·W A Ray
Dec 8, 1990·BMJ : British Medical Journal·R WasnichJ Vogel
Feb 1, 1990·The New England Journal of Medicine·A Z LaCroixA M Ostfeld
Oct 1, 1990·American Journal of Epidemiology·D P KielP W Wilson
Mar 1, 1989·American Journal of Public Health·S Greenland
Dec 29, 1988·The New England Journal of Medicine·M E TinettiS F Ginter
Apr 1, 1982·Metabolism: Clinical and Experimental·I TransbølP McNair
Aug 1, 1981·Computers and Biomedical Research, an International Journal·G R Howe, J Lindsay
Jun 30, 1994·The New England Journal of Medicine·D S SiscovickE H Wagner
Dec 1, 1993·Scandinavian Journal of Social Medicine·O P RyynänenV Saano

❮ Previous
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Citations

Nov 23, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M J BollandI R Reid
Sep 18, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F J A Penning-van BeestR M C Herings
May 29, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·V RabendaJ-Y Reginster
Feb 11, 2004·Joint, Bone, Spine : Revue Du Rhumatisme·Isabelle Legroux-GerotBernard Cortet
Jan 23, 1999·Clinical Therapeutics·S Hennessy
May 3, 2008·Endocrine Reviews·Sundeep KhoslaEric Orwoll
Feb 5, 2010·The Journal of Clinical Endocrinology and Metabolism·Sander PouwelsFrank de Vries
Sep 17, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A LalandeM C De Vernejoul
Feb 24, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A LalandeM C De Vernejoul
May 28, 2014·Archives of Physical Medicine and Rehabilitation·Claudia Nassaralla, Kenneth W Lyles
Dec 20, 2011·Calcified Tissue International·Arief LalmohamedFrank de Vries
Oct 23, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M E L ArbouwF de Vries
Jan 22, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S PouwelsF de Vries
Feb 25, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M W M van den BrandF de Vries
Oct 17, 2008·Current Medical Research and Opinion·Willemijn M MeijerRon M C Herings
Dec 3, 2010·Kidney International·Khashayar SakhaeeOrson W Moe
Oct 12, 2010·Clinics in Geriatric Medicine·Nichola BoyleRobert G Cumming
Dec 15, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C KruseP Vestergaard
Oct 1, 2015·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Kris van KeulenWilma Knol
Dec 3, 2003·Journal of Internal Medicine·P C SouvereinH G M Leufkens
Mar 7, 2012·Pharmacoepidemiology and Drug Safety·Marloes T BazelierFrank de Vries
May 29, 2004·American Journal of Preventive Medicine·Ludmila N BakhirevaDeborah J Morton
Apr 17, 2015·Archives of Disease in Childhood·Soulmaz Fazeli FarsaniAukje K Mantel-Teeuwisse
Oct 18, 2016·Pediatric Pulmonology·Fariba AhmadizarAnke H Maitland-van der Zee
Oct 7, 2011·The Cochrane Database of Systematic Reviews·Koko Aung, Thwe Htay
Aug 17, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L I van de VenP K Janssen
Jun 4, 2014·Antimicrobial Agents and Chemotherapy·Soulmaz Fazeli FarsaniAukje K Mantel-Teeuwisse
Sep 26, 2006·Pharmacoepidemiology and Drug Safety·Frank de VriesTjeerd-Pieter van Staa
Jan 27, 2007·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Bahi TakkoucheMahyar Etminan
Oct 20, 2017·BMC Geriatrics·Christina SommerauerAndreas Sönnichsen
Dec 26, 2019·Scientific Reports·Tesfaye Getachew CharkosShuman Yang
Nov 30, 2010·Acta Orthopaedica. Supplementum·Theis Muncholm Thillemann
Feb 10, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·I J A de BruinF de Vries
Apr 18, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H TaipaleA-M Tolppanen
Oct 14, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D CanoyK Rahimi

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