CuS nanoparticles-enhanced luminol-O2 chemiluminescence reaction used for determination of paracetamol and vancomycin.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Mortaza IranifamHaider A J Al Lawati

Abstract

A new chemiluminescence (CL) method was proposed to measure two widely used drugs, including paracetamol (PCM) and vancomycin (VAN). The CL reaction used was the CuS nanoparticles (CuS NPs)-luminol-O2 system. In this system, CuS NPs played the role of catalyst and increased the CL intensity. CuS NPs were easily synthesized by quick-precipitation. CuS NPs were characterized by spectroscopic techniques, and the mean size of NPs was estimated to be about 9 nm. In the developed CL methods, PCM and VAN decreased the CL intensity. In the proposed method, the linear concentration ranges were 4.0 × 10-5-4.0 × 10-4 mol L-1 of PCM and 2.0 × 10-5-6.0 × 10-4 mol L-1 of VAN. The limit of detections were 2.9 × 10-5 mol L-1 and 8.9 × 10-6 mol L-1 for PCM and VAN, respectively. The relative standard deviations (RSD) of the CL method were 2.99 and 4.31 (n = 6) for the determination of 3.0 × 10-4 mol L-1 PCM and VAN, respectively. It was also shown that the CL methods can measure PCM and VAN concentrations in various real samples.

References

Nov 6, 2012·Luminescence : the Journal of Biological and Chemical Luminescence·Mortaza Iranifam
Jan 8, 2013·Journal of Agricultural and Food Chemistry·Xiaodan ZhangYuming Huang
Jan 1, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·A R KhataeeS W Joo
Jan 18, 2016·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Siniša GlavanovićVladislav Tomišić
Oct 21, 2016·Nanoscale Research Letters·Zezhong LiuHuiyun Chang
Feb 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mahsa Haddad Irani-NezhadYasin Orooji
Apr 2, 2020·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Yasin OroojiSang Woo Joo
May 18, 2020·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Paola MillaSilvia Arpicco
May 17, 2021·Food Research International·Francine Kerstner de OliveiraJaqueline Garda Buffon

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