Cushing syndrome and pregnancy: a propos of a malignant adrenocortical carcinoma

Gynécologie, obstétrique & fertilité
L HomerV Kerlan

Abstract

Cushing's syndrome is a rare condition in the general population (1/1000000) and is even less common during pregnancy. We report the case of a patient cared at 27 weeks of gestation (wg) for hypertension and electolyte disturbances. Cushing's syndrome was confirmed by salivary cortisol and ACTH assessment. RMN revealed a 9 cm left adrenal tumor. Severe hypertension and electolyte disturbances on the one hand, and diagnostic uncertainty on the other hand, imposed adrenalectomy at 29 wg. Twelve days later, fetal distress led to a caesarian section and birth of a well being male baby.

References

Sep 1, 1990·The Journal of Clinical Endocrinology and Metabolism·E M ScottG C Lachelin
Apr 12, 2000·Kidney International·J R SecklM J Nyirenda
May 7, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·A L Fowden, A J Forhead
Jun 29, 2004·Archives of Gynecology and Obstetrics·Vorapong PhupongPornthip Ultchaswadi
Apr 14, 2005·Endocrine Reviews·John R Lindsay, Lynnette K Nieman
Jul 6, 2006·Endocrine Journal·Kinshi KosakaKosei Hirakawa

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Citations

Jul 25, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M DarocasA Cano

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