PMID: 3748930Jul 1, 1986Paper

Cushing's syndrome--transitory immune deficiency state?

Postgraduate Medical Journal
M I WürzburgerB Pendić

Abstract

A 28 year old female patient with Cushing's syndrome due to an adrenal adenoma also suffered from recurrent urinary infections (proteus), tonsillitis (streptococcus), permanent candidiasis and perimandibular abscess (Staphylococcus pyogenes). Suppression of cellular and humoral immunity was confirmed by in vitro tests. After successful right adrenalectomy the clinical signs of Cushing's syndrome disappeared and no evidence of either bacterial or fungal infection were noted one year postoperatively. Immunological tests showed the restitution of both cellular and humoral immunity. The course of the disease in the patient supports the idea that Cushing's syndrome might be considered as a transitory immune deficiency state.

References

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Citations

Sep 13, 2011·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Hiroyuki Kataoka
Dec 5, 2003·Lancet·Michail S Lionakis, Dimitrios P Kontoyiannis
Jan 21, 2010·Endocrine Reviews·Mark SherlockPaul M Stewart
Jun 13, 2015·Endocrine Reviews·Rosario PivonelloAnnamaria Colao
May 16, 1998·Diagnostic Cytopathology·P A Drew, K Takezawa
Sep 23, 2014·European Journal of Pediatrics·Alexandra GkourogianniConstantine A Stratakis
Jan 20, 2021·Cellular and Molecular Life Sciences : CMLS·Deepika WattsBen Wielockx

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