PMID: 9539563Apr 16, 1998Paper

Customized gynecologic interstitial implants: CT-based planning, dose evaluation, and optimization aided by laparotomy

International Journal of Radiation Oncology, Biology, Physics
A EisbruchJ A Roberts

Abstract

Interstitial perineal implants may be utilized to deliver a high local radiation dose in the treatment of advanced gynecologic malignancies. Lack of knowledge of the precise anatomic relationships between the implant and the target and critical organs may limit efficacy and increase complication risks. Computed tomography (CT)-based planning, dose evaluation, and optimization of customized interstitial implants, aided by laparotomy, have been developed to overcome these limitations. Twenty patients with locally advanced gynecologic malignancies treated between May 1990 to October 1996 with external irradiation and one or two implants. Interstitial implants were performed when intracavitary brachytherapy was judged to be inadequate or when the response to external radiation and an intracavitary implant was not satisfactory. Customized interstitial implants were planned using preimplantation CT to determine catheter angles and paths that best implanted the target while avoiding pelvic bones and organs. Laparotomy aimed at lysing bowel adhesions, placement of omental carpet, and refining needle placement. Postimplantation CT was used for loading optimization and dose evaluation. Catheter angles 15-25 degrees were found to adequate...Continue Reading

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Citations

Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·Subir NagUNKNOWN American Brachytherapy Society
Mar 2, 2002·International Journal of Radiation Oncology, Biology, Physics·I-Chow J HsuJean Pouliot
Nov 7, 2002·International Journal of Radiation Oncology, Biology, Physics·Etienne LessardJean Pouliot
Feb 16, 2005·Current Opinion in Obstetrics & Gynecology·Niloy Ranjan Datta
Apr 6, 2004·Brachytherapy·Beth A Erickson
Jan 17, 2012·Hematology/oncology Clinics of North America·Akila N Viswanathan
Jan 24, 2012·Brachytherapy·Akila N ViswanathanUNKNOWN American Brachytherapy Society
Aug 22, 2009·International Journal of Radiation Oncology, Biology, Physics·Anand P ShahThomas W Zusag
Jul 22, 2009·International Journal of Radiation Oncology, Biology, Physics·Akila N Viswanathan, Beth A Erickson
Nov 23, 2006·Brachytherapy·Sushil BeriwalRobert P Edwards
Jul 15, 2006·International Journal of Radiation Oncology, Biology, Physics·Akila N ViswanathanClare Tempany
May 13, 2006·International Journal of Radiation Oncology, Biology, Physics·Christian KirisitsRichard Pötter
Jul 25, 2014·Brachytherapy·Lars FokdalJacob Christian Lindegaard
Jun 20, 2015·Brachytherapy·Mark J AmsbaughMoataz El-Ghamry
May 18, 2012·International Journal of Radiation Oncology, Biology, Physics·Larissa J Lee, Akila N Viswanathan
Sep 20, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Lars FokdalJacob Christian Lindegaard
Aug 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A EisbruchT S Lawrence

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