PMID: 9539364Apr 16, 1998Paper

Cutaneous and systemic necrotizing vasculitis in swine

Veterinary Pathology
S ThibaultR Magar

Abstract

A systemic vasculitis involving particularly the skin and kidneys has been recently described in swine under the name dermatitis/nephropathy syndrome. Twelve pigs with gross cutaneous lesions typical of this condition were necropsied, and morphologic, immunohistochemical, microbiologic, and epidemiologic characteristics were studied. The pigs were divided into three groups comprising eight pigs with acute lesions, two with chronic lesions, and two with acute lesions kept for sequential skin biopsies. Acute skin lesions consisted of round to irregular, red to purple macules and papules that often coalesced to form large, irregular patches and plaques. With time, the lesions became covered by crusts and faded gradually, sometimes leaving scars. Characteristic distribution included the perineal area of the hindquarters, limbs, dependent parts of the abdomen and thorax, and margins of the ears. In the acute phase of the disease, necrotizing and leucocytoclastic vasculitis of small-caliber blood vessels were observed within the dermis and panniculus and in various extracutaneous locations such as the renal pelvis and synovial membranes. All pigs had macroscopic evidence of pneumonia and generalized lymphadenopathy. Microscopically, ...Continue Reading

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Citations

Jan 27, 2004·Veterinary Microbiology·Joaquim SegalésMariano Domingo
Jan 27, 2004·Veterinary Microbiology·J EllisG M Allan
Jul 14, 1999·Journal of Virological Methods·R LarochelleR Magar
Sep 12, 2000·International Journal of Cardiology·A J Dal Canto, H W Virgin
Apr 6, 2006·Animal Health Research Reviews·Joaquim SegalésMariano Domingo
Apr 15, 2008·New Zealand Veterinary Journal·A C Johnstone, D E B Lawton
Jan 23, 1999·Current Opinion in Rheumatology·A J Dal Canto, H W Virgin
Sep 29, 2009·Journal of Veterinary Internal Medicine·J GillespieV Buechner-Maxwell
Nov 26, 2008·Best Practice & Research. Clinical Rheumatology·Nicolò Pipitone, Carlo Salvarani
Apr 26, 2005·The Veterinary Journal·C Chae
Aug 13, 2015·Viral Immunology·Vasileios G PapatsirosDominiek Maes
Jun 14, 2002·Acta Veterinaria Hungarica·T MolnárA Dán
Jun 14, 2012·Veterinary Pathology·T Opriessnig, I Langohr
Jul 19, 2006·Veterinary Pathology·K A MarateaG W Stevenson
Nov 14, 2007·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Tanja OpriessnigPatrick G Halbur
Jun 1, 2000·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M Y GulbaharH Icen
Jun 19, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·K SaoulidisP A Papoutsis
Nov 7, 2002·The Veterinary Record·C ChoiC Chae
Nov 27, 2002·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·J R ThomsonS H Done
Jan 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Caitlin D LemkeJohn E Butler
Dec 24, 2004·La Presse médicale·Pascal Cohen, Loïc Guillevin
Jun 10, 2021·Acta Veterinaria Hungarica·Branislav KureljušićChristiane Weissenbacher-Lang

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