Cutaneous Aspergillus ustus in a lung transplant recipient: emergence of a new opportunistic fungal pathogen

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Parsia A VagefiCamille N Kotton

Abstract

Opportunistic fungal infections remain a significant complication in immunosuppressed patients, especially those having undergone solid-organ transplantation. We report a 39-year-old patient who represents the second case of cutaneous Aspergillus ustus infection in a solid-organ transplant recipient, and the first documented case after lung transplantation. The patient's cutaneous lower extremity aspergillosis responded to a combination of intravenous liposomal amphotericin B, caspofungin and topical terbinafine cream, with a concomitant reduction in immunosuppression. A. ustus is an emerging opportunistic fungal pathogen in transplant recipients.

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Citations

Jul 2, 2009·Hand : Official Journal of the American Association for Hand Surgery·Olushola OlorunnipaCatherine M Curtin
Aug 9, 2008·Current Infectious Disease Reports·Camille Nelson Kotton
Mar 20, 2009·Medical Mycology·Ana Alastruey-IzquierdoJuan L Rodriguez-Tudela
Jan 7, 2011·Medical Mycology·Gunhild HageskalIda Skaar
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Aug 3, 2010·Infectious Disease Clinics of North America·Shawn P E NishiSteve Duncan
Jun 15, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Miguel M CabadaVincent G Valentine
Jun 2, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Cinzia LastoriaFederica Meloni
Feb 10, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Víctor MonforteAntonio Román
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Jun 16, 2011·Mycoses·Marisa H Miceli, Samuel A Lee
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Oct 12, 2016·Microbiology Spectrum·Anne Spichler MoffarahDavid G Armstrong

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Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

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