Cutaneous CD30-Positive Lymphoproliferative Disorders

Surgical Pathology Clinics
Werner Kempf

Abstract

Cutaneous CD30+ lymphoproliferative disorders are the second most common types of cutaneous T-cell lymphomas. They represent a well-defined spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL), and borderline lesions. They share the expression of CD30 as a common phenotypic hallmark, but they differ in their clinical presentation, course, and histologic features. New variants have been recently identified, including CD8+ epidermotropic LyP type D, angioinvasive LyP type E, and ALK-positive pcALCL. This review describes clinical, histopathologic, and phenotypic variants; their differential diagnoses (benign and malignant); and the role of CD30 as a diagnostic, prognostic, and therapeutic marker.

References

Oct 1, 1992·Journal of the American Academy of Dermatology·M A BarnadasJ M de Moragas
Dec 15, 1992·Cancer·H H WangM E Kadin
Feb 1, 1990·The American Journal of Dermatopathology·L RequenaE Sánchez Yus
Nov 1, 1995·Journal of the American Academy of Dermatology·G M ZirbelN B Esterly
Apr 1, 1995·The American Journal of Surgical Pathology·K P MannH Ratech
Sep 1, 1993·The American Journal of Surgical Pathology·M C KinneyM E Kadin
Dec 22, 1999·The British Journal of Dermatology·J J ScarisbrickR Russell-Jones
Sep 5, 2001·The British Journal of Dermatology·M W BekkenkR Willemze
Apr 26, 2002·Journal of Cutaneous Pathology·Enrique HerreraPurificación Sánchez
Jul 9, 2002·Journal of Cutaneous Pathology·Werner KempfMarshall E Kadin
Jul 2, 2003·Dermatology : International Journal for Clinical and Investigative Dermatology·H YurtseverR H Laeng
Sep 6, 2003·International Journal of Dermatology·Oya OguzCuyan Demirkesen
Apr 21, 2004·Archives of Dermatology·Laila El Shabrawi-CaelenLorenzo Cerroni
Dec 18, 2004·Dermatology : International Journal for Clinical and Investigative Dermatology·Ramon M PujolAgustí Alomar
Feb 5, 2005·Blood·Rein WillemzeChris J L M Meijer
Mar 21, 2006·Journal of the American Academy of Dermatology·Farhana E RavatRobin Russell-Jones
Jul 20, 2007·The British Journal of Dermatology·X Garcia-NavarroA Alomar
Jul 12, 2008·Journal of Cutaneous Pathology·Betina WernerLorenzo Cerroni
Nov 27, 2008·The American Journal of Dermatopathology·Katalin FerencziKord Honda
Feb 7, 2009·Clinical and Experimental Dermatology·J H KunishigeM Duvic
Apr 10, 2009·Hematological Oncology·Alessandro FornariGiorgio Inghirami
Jul 7, 2009·Journal of the American Academy of Dermatology·Aieska de SouzaRokea A el-Azhary
Oct 1, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Madeleine DuvicYoun H Kim
Oct 9, 2009·The Journal of Investigative Dermatology·Anne Pham-LedardJean-Philippe Merlio
Nov 10, 2009·The American Journal of Surgical Pathology·James T EdingerSteven H Swerdlow
Mar 27, 2010·Journal of Cutaneous Pathology·Lei WangTianwen Gao
Nov 5, 2010·The New England Journal of Medicine·Anas YounesAndres Forero-Torres

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Citations

Oct 5, 2015·Dermatologic Clinics·Werner Kempf, Christina Mitteldorf
Oct 30, 2014·Journal of Cutaneous Pathology·Aieska De SouzaWerner Kempf
Feb 27, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·W KempfK Kerl
Apr 7, 2016·JAAD Case Reports·Kunal AngraIfe J Rodney
Jan 16, 2015·Der Pathologe·W Kempf, C Mitteldorf
Aug 12, 2016·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Iris WieserMadeleine Duvic
Aug 12, 2016·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Iris WieserMadeleine Duvic
Oct 21, 2016·Journal of Cutaneous Pathology·Kathryn J MartiresDavid S Cassarino
Jul 8, 2017·Pediatric Dermatology·Jennifer Shastry, Heather Ciliberto
Jul 19, 2018·International Journal of Dermatology·Laura Macías-GarcíaJuan J Ríos-Martín
Jan 4, 2019·Archives of Pathology & Laboratory Medicine·Gabriel Habermehl, Jennifer Ko
Jun 27, 2019·Journal of Cutaneous Pathology·Christina Mitteldorf, Werner Kempf
Jun 6, 2019·Blood·Michi M Shinohara, Andrei Shustov
Aug 23, 2019·The American Journal of Dermatopathology·Leonardo A TjahjonoNneka I Comfere
Oct 9, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·R Fernández-de-MisaT Estrach
Nov 13, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·R C MelchersK D Quint
Jan 14, 2020·International Journal of Dermatology·Cristina López-SánchezLluís Puig
May 12, 2018·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Christina MitteldorfWerner Kempf
Jul 9, 2020·Journal of Cutaneous Pathology·Antonio Subtil, Alejandro A Gru
May 5, 2018·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Christina MitteldorfWerner Kempf
Oct 11, 2017·Clinical and Experimental Dermatology·R Fernández-de-MisaT Estrach
Oct 19, 2020·The Australasian Journal of Dermatology·Matthew J VerheydenKaren Cheung
Nov 28, 2020·The Journal of Dermatology·Mikio OhtsukaMakoto Sugaya

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