Cutaneous damage after acute exposure to ionizing radiation: decisive for the prognosis of radiation accident victims

Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
H DörrV Meineke

Abstract

The cutaneous radiation syndrome includes all deterministic effects on the skin and visible parts of the mucosa from ionizing radiation. The Intensity and duration of radiation-induced skin symptoms depend on the kind and quality of ionizing radiation. The aim of this study was the investigation of the importance of the time of the development of radiation induced-skin effects on the prognosis of radiation accident victims. Clinical data about radiation accident victims from the database SEARCH were used. 211 cases with good documentation regarding radiation-induced skin effects were selected. From these 211 patients, 166 survived the acute phase of the acute radiation syndrome, while 45 died during the acute phase. Among those patients who did not survive the acute phase, 82.2 % showed their first documented radiation-induced skin symptoms during the first 3 days after radiation exposure. Of those patients whose first documented radiation-induced skin symptoms appeared on or after day four, 94.2 % survived the acute phase. The time to the occurrence of the first radiation-induced skin effects is diagnostically significant. The skin plays an important role in the clinical course of radiation syndromes and in the development of ...Continue Reading

References

Apr 1, 1990·International Journal of Radiation Biology·J W Hopewell
Sep 21, 2000·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·P GottlöberR U Peter
Nov 30, 2000·Radiation and Environmental Biophysics·I FrieseckeT M Fliedner
Mar 24, 2007·Experimental Hematology·Kerstin Müller, Viktor Meineke
Nov 26, 2009·International Journal of Radiation Oncology, Biology, Physics·Harald PaganettiBryan Bednarz
May 7, 2010·Health Physics·Marc BenderitterJean Jacques Lataillade
Oct 12, 2011·Disaster Medicine and Public Health Preparedness·Nicholas DainiakViktor Meineke

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