Cutaneous epithelioid angiomatous nodule: a case series and proposed classification

The American Journal of Dermatopathology
O P SanguezaL Requena

Abstract

Cutaneous epithelioid angiomatous nodule is a peculiar and recently recognized vascular proliferation. Clinically, these lesions affect different areas of the body and histologically are characterized by a well-circumscribed, mainly unilobular, solid proliferation of endothelial cells with prominent epithelioid features. The cytoplasm is abundant and eosinophilic, and many of the neoplastic cells contain prominent vacuoles. Inflammatory infiltrates are variable. All the cases reported thus far have followed a benign course. We report 10 additional cases of this curious entity, including 2 which presented in an eruptive fashion and 5 that were located on the head and neck. We also discuss the histological differential diagnoses with other epithelioid proliferations and propose categorization within the spectrum of epithelioid hemangioma.

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Citations

May 23, 2008·The American Journal of Dermatopathology·Angel Fernandez-Flores
Sep 21, 2011·The American Journal of Dermatopathology·Peter G PavlidakeyStephen C Somach
Nov 10, 2011·Pediatric Dermatology·Eulalia BaselgaIlona J Frieden
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Jul 15, 2009·Pathology, Research and Practice·Zhi-Jun SunFernand Mac-Moune Lai
Feb 18, 2009·Journal of Cutaneous Pathology·Narciss Mobini
Jul 7, 2010·Journal of Cutaneous Pathology·Tatsushi ShiomiHisao Ito
Feb 18, 2011·Journal of Cutaneous Pathology·Seema KaushalUttam Kumar
Aug 25, 2015·Surgical Pathology Clinics·Jennifer S Ko, Steven D Billings
Mar 3, 2015·Auris, Nasus, Larynx·Wai Keat WongChing Wern Ong
Sep 7, 2016·Journal of Cutaneous Pathology·C NikolaidouS Piana
Dec 24, 2016·The American Journal of Surgical Pathology·Yin P HungJason L Hornick
Mar 29, 2016·World Journal of Methodology·Mar Llamas-VelascoThomas Mentzel
Dec 22, 2017·The American Journal of Surgical Pathology·Mar Llamas-VelascoHeinz Kutzner
Sep 28, 2017·The American Journal of Dermatopathology·Angel Fernandez-Flores, David S Cassarino
Feb 15, 2019·Advances in Anatomic Pathology·Wonwoo Shon, Steven D Billings
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Feb 26, 2020·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Boštjan LuzarEduardo Calonje
Oct 22, 2020·The American Journal of Dermatopathology·Mar Llamas-Velasco, Thomas Mentzel
Jan 20, 2021·The American Journal of Dermatopathology·Patricia AlvarezOmar Sangueza

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