Cutaneous epithelioid hemangioendothelioma on the sole of a child

Pediatric Dermatology
Carmen Carranza-RomeroLuis Requena

Abstract

Epithelioid hemangioendothelioma (EHE) has been considered to be a low-grade malignant vascular neoplasm, although follow-up of recent series has demonstrated that EHE involving the skin and soft tissues should be better regarded as a fully malignant vascular tumor since it has more metastatic potential than previously thought. We report a case of an EHE involving the left sole of 6-year-old boy, the youngest patient with cutaneous EHE described to date. Immunohistochemical studies demonstrated a lymphatic endothelial line of differentiation for neoplastic cells. Cutaneous EHE is rare in childhood, with only five previously described cases.

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Citations

Jul 1, 2017·The Australasian Journal of Dermatology·Hyun Jee KimJun Young Lee
May 25, 2016·Archives of Plastic Surgery·Hyung-Suk RoWoo-Sung Moon
Mar 2, 2019·European Journal of Medical Research·Xin WuXiaodong He

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