Cutaneous events during treatment of chronic inflammatory joint disorders with anti-tumour necrosis factor alpha: a cross-sectional study

Journal of the European Academy of Dermatology and Venereology : JEADV
A C DavaineL Misery

Abstract

Anti-tumour necrosis factors (anti-TNF) are more and more used, but the rate of skin adverse events is not known. The aim was to assess the number of skin infections and other dermatoses in patients treated with anti-TNFalpha. One hundred eighty-seven patients suffering from rheumatoid arthritis or ankylosing spondylitis underwent a dermatological exam. Patients with anti-TNF were compared with those without this treatment in a prospective transversal study. Among them, 59 patients were treated with anti-TNFalpha and steroids were prescribed in 100 cases. There was no difference in the prevalence of skin infections or eczema or tumours. Skin drug reactions were observed in six patients. Infections by dermatophytes appear very frequent, approaching 70% in both groups. This study shows that skin infections (or other skin diseases) are not more frequent in these patients. No differences were observed in infections (bacterial fungal, parasital or viral), tumours, psoriasis or the manifestations of atopic dermatitis. Nonetheless, a long-term survey might be interesting, especially about skin tumours.

References

Jul 1, 1987·Arthritis and Rheumatism·J P VandenbrouckeJ Weber
Mar 21, 2002·The British Journal of Dermatology·L MiseryC Alexandre
Jun 25, 2002·Annals of the Rheumatic Diseases·D C Baumgart, A U Dignass
Oct 16, 2002·Annals of the Rheumatic Diseases·M RudwaleitJ Braun
Jan 28, 2003·Rheumatology International·Ali BicerCanan Erdogan
Aug 2, 2003·Journal of the American Academy of Dermatology·Daniel Burge
Nov 25, 2003·The New England Journal of Medicine·Craig L LeonardiUNKNOWN Etanercept Psoriasis Study Group
Dec 17, 2003·Archives of Dermatology·Alice B GottliebRalph Zitnik
May 6, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R S WallisD O Beenhouwer
Sep 25, 2004·Journal of the American Academy of Dermatology·Alice B GottliebAlan Menter
Jul 13, 2005·The Australasian Journal of Dermatology·Yee J Tai, Robert Kelly
Jul 30, 2005·Arthritis and Rheumatism·P P SfikakisA Stratigos
Oct 6, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·A M ThielenJ-H Saurat
May 8, 2007·Annales de dermatologie et de vénéréologie·D LebasE Delaporte

❮ Previous
Next ❯

Citations

Dec 29, 2010·Clinical Reviews in Allergy & Immunology·Laurent Misery
Mar 16, 2011·Clinical Reviews in Allergy & Immunology·Irene PontikakiPier Luigi Meroni
Jul 21, 2012·Der Internist·R Treudler, J C Simon
Jul 21, 2009·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Regina Treudler
Jul 21, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·J RingUNKNOWN Global Allergy and Asthma European Network
Aug 27, 2014·Clinical and Experimental Dermatology·S MateoJ Toribio
Nov 5, 2016·International Journal of Dermatology·Ana Filipa PedrosaCarmen Lisboa
Aug 30, 2016·The Journal of Dermatological Treatment·Mio NakamuraTina Bhutani
Oct 13, 2011·Nature Reviews. Rheumatology·Robert S Woodrick, Eric M Ruderman
Jan 31, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A Al-JanabiR B Warren

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Dermatology : International Journal for Clinical and Investigative Dermatology
S HakimiA Le Quellec
Dermatology : International Journal for Clinical and Investigative Dermatology
Christina AntoniouAndreas D Katsambas
Best Practice & Research. Clinical Rheumatology
Manuel Ramos-CasalsMunther A Khamashta
© 2022 Meta ULC. All rights reserved