PMID: 6984639Jan 1, 1982Paper

Cutaneous immunoblastic T-cell lymphoma

Archives of Dermatological Research
C SchmoeckelO Braun-Falco

Abstract

The case of a 69-year-old male patient with an unusual type of malignant lymphoma is presented. Clinically, it was at first characterized by follicular papules and erythematous patches, later, by the development of cutaneous tumors and enlarged lymph nodes, and by a severe, finally excruciating pruritus. Treatment with PUVA (psoralen-ultraviolet-A) combined with 40--80 mg prednisolone and then with chemotherapy [COPP regimen (cyclophosphamide, vincristine, procarbacine, prednisone), high-dosage methotrexate followed by citrovorum factor rescue] was not successful. The patient died of pneumonia 2.5 years after the onset of the first clinical symptoms. An immunoblastic infiltrate was observed histologically and electromicroscopically in the initial lesions of the skin. Therefore, the diagnosis of a cutaneous immunoblastic T-cell lymphoma was tentatively made at the beginning, which was later confirmed in numerous biopsies and laboratory investigations. Immunocytologically and enzymecytochemically, the infiltrating cells were shown to be immature T cells; in the lymph nodes, numerous immunoblasts and large Sézary cells was observed in the peripheral blood, though there were no very large Sézary cells or blast cells. In the autopsy...Continue Reading

References

Apr 1, 1978·Archives of Dermatology·C I Harrington, D N Slater
Nov 1, 1979·Archives of Dermatological Research·C SchmoeckelO Braun-Falco
Feb 23, 1979·Archives of Dermatological Research·C SchmoeckelO Braun-Falco
Aug 1, 1978·The Journal of Dermatologic Surgery and Oncology·H GoldschmidtH H Schoefinius
Nov 1, 1975·Journal of Immunological Methods·C J Meijer, J Lindeman
Dec 31, 1975·Virchows Archiv. A, Pathological Anatomy and Histology·E W Schwarze, P Ude
Oct 1, 1975·The Journal of Investigative Dermatology·A W van LeeuwenJ C de Man
Jan 1, 1973·Transplantation Reviews·E M ShevachI Green
Mar 1, 1981·The British Journal of Dermatology·E M van der LooC J Meijer
Jan 15, 1981·Cancer·T V ColbyR T Hoppe

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Citations

Jan 1, 1987·Archives of Dermatological Research
Jan 1, 1984·Archives of Dermatological Research·S C van der PutteJ A van Unnik
Apr 1, 1984·The Journal of Dermatologic Surgery and Oncology·M L GeertsO Braun-Falco
May 1, 1988·Acta Pathologica Japonica·H SegamiH Wakasa

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