PMID: 8600806Aug 1, 1995Paper

Cutaneous intraneural glomus tumor

The American Journal of Dermatopathology
E Calonje, C D Fletcher

Abstract

The unusual occurrence of a glomus tumor within a small, deep dermal nerve is reported. This phenomenon has been described previously only once in the literature. The lesion appeared as a painful cutaneous nodule in the shoulder of a 67-year-old woman. Microscopically, a typical solid, smooth muscle actin-positive glomus tumor was seen, encircled completely by neural tissue in the deep dermis. There was no extension of the tumor beyond the nerve. Immunohistochemically, the nerve fibers surrounding and within the tumor were positive for S-100 protein and neurofilament. The presence of perineurium surrounding the glomus tumor was confirmed by a layer of epithelial membrane antigen-positive cells. In view of the absence of normal glomus bodies in the nerves, an origin from a less specialized perivascular cell is proposed.

Citations

Feb 5, 2008·Journal of Neurosurgery·Bernd W ScheithauerYao-Shi Fu
Mar 18, 2017·Skeletal Radiology·Rajendra KumarJustin E Bird
Jul 6, 2018·BMJ Case Reports·Sumetha RajendranStuart Gillett
Feb 15, 2014·Journal of Korean Neurosurgical Society·Dong Sun ParkChang-Taek Moon
Jul 1, 1997·Journal of Cutaneous Pathology·E AceboF Arce
Aug 1, 1996·The American Journal of Dermatopathology·P Polk, P J Biggs
Apr 5, 2011·Clinical and Experimental Otorhinolaryngology·Young Sam YooHyun-Jung Kim
Dec 23, 2017·Journal of Cutaneous Pathology·Siobhan MuthiahAkhtar Husain
Feb 16, 2020·BMJ Case Reports·Vikram SinghNandita Kakkar
Dec 4, 2020·World Journal of Clinical Cases·Hai-Ying ZhouHui Lu
Jun 18, 2021·Case Reports in Orthopedics·Luís VieiraManuel Ribeiro da Silva
Jan 7, 1998·Journal of the American Academy of Dermatology·L Requena, O P Sangueza

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