Cutaneous manifestations of common liver diseases

Journal of Clinical and Experimental Hepatology
Sunil Dogra, Rashmi Jindal

Abstract

Skin functions as a window to our overall health and a number of systemic diseases result in various cutaneous changes. Knowledge of these manifestations helps in suspecting an underlying systemic illness. Cutaneous abnormalities are quite common in patients with liver diseases and this article aims to focus on these dermatoses. Cutaneous manifestations seen in patients with liver disease though common are nonspecific. They can also be seen in patients without liver diseases and generally do not indicate about a specific underlying hepatic disorder. The presence of a constellation of signs and symptoms is more useful in pointing toward an underlying hepatobiliary condition. The commonest symptom in patients with liver disease is pruritus which is often protracted and disabling. Other common features include spider angiomas, palmar erythema, paper money skin, xanthelasmas, pigmentary changes, and nutritional deficiencies. In this article, first the common cutaneous manifestations that may be associated with liver disorders are discussed and then common liver diseases with their specific cutaneous findings are discussed. Cutaneous abnormalities may be the first clue to the underlying liver disease. Identifying them is crucial for...Continue Reading

References

Apr 1, 1970·The American Journal of Clinical Nutrition·C M LeevyH Baker
Mar 1, 1972·Gut·G M MurphyB H Billing
Aug 1, 1970·British Medical Journal·I M Murray-LyonR Williams
Apr 21, 1984·Lancet·M Holzberg, H K Walker
Dec 1, 1981·European Journal of Clinical Investigation·M BahnsenU A Brodthagen
Jun 1, 1982·The British Journal of Dermatology·R A Graham-BrownS Sherlock
Nov 1, 1982·The British Journal of Dermatology·F C PowellE R Dickson
Jul 1, 1996·Journal of the American Academy of Dermatology·F AllegueN Alfonsín
Apr 1, 1996·International Journal of Dermatology·M el Darouti, M Abu el Ela
Nov 21, 1996·The New England Journal of Medicine·M M Kaplan
Feb 1, 1997·Seminars in Liver Disease·J Heathcote
Jul 1, 1997·The Journal of Dermatology·B S ParkJ A Kim
May 8, 1999·Clinical and Experimental Dermatology·Y KubotaJ Nakayama
Jul 20, 1999·Journal of the American Academy of Dermatology·T Y ChuangC Lewis
Mar 25, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E J Heathcote
Jun 23, 2000·Journal of the American Academy of Dermatology·K E Smith, N A Fenske
Jun 28, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J J ArrietaV Carreno
Sep 14, 2001·Journal of Gastroenterology and Hepatology·N KumarB S Anand
Sep 25, 2001·Journal of the American Academy of Dermatology·S Al-Khenaizan
Oct 17, 2001·Annals of the Rheumatic Diseases·B MarasiniP Ferrari
Jan 16, 2002·Current Opinion in Rheumatology·Patrice CacoubLaurent Alric
Jun 13, 2002·Mayo Clinic Proceedings·Jill WaalenErnest Beutler
Jul 30, 2002·Dermatology : International Journal for Clinical and Investigative Dermatology·Takahiro SatohKiyoshi Nishioka
Sep 5, 2002·Seminars in Neonatology : SN·Giovanna Bertini, Firmino F Rubaltelli
Mar 27, 2003·Alimentary Pharmacology & Therapeutics·M MelaA K Burroughs
Apr 19, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·R Gimenez-García, J L Pérez-Castrillón
Jun 6, 2003·The British Journal of Dermatology·W NishieT Kusama
Jan 22, 2005·Pediatric Dermatology·Maria Amelia GarciaMaria Teresa de Davila
Dec 14, 2005·Current Opinion in Rheumatology·Clodoveo Ferri, Maria Teresa Mascia
Dec 24, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Janneke M StapelbroekRoderick H J Houwen
Feb 9, 2006·The American Journal of Gastroenterology·Meri KoulentakiElias A Kouroumalis
Apr 6, 2006·Archives of Disease in Childhood·S M FinnB Bourke
Apr 29, 2006·American Journal of Therapeutics·Glenn GandelmanMelvin B Weiss
Jun 27, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Ulrich BeuersThomas Pusl

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Citations

Jan 1, 2013·International Journal of Food Science·Nawraj RummunVidushi S Neergheen-Bhujun
Jul 17, 2015·The Nurse Practitioner·Tracy Gasson, Kathleen Klein
Oct 11, 2017·Clinical Reviews in Allergy & Immunology·Benedetta Terziroli Beretta-PiccoliCarlo Mainetti
Jun 28, 2016·Clinical Liver Disease·Carilyn Wieland
Aug 5, 2020·Scientific Reports·Agnieszka ŻelaźniewiczBogusław Pawłowski
Sep 23, 2020·Diagnostics·Mrigendra B KarmacharyaChandra M Sehgal

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