Cutaneous manifestations of coronavirus disease 2019 in 458 confirmed cases: A systematic review

Journal of Family Medicine and Primary Care
Rashmi Jindal, Payal Chauhan

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has affected the whole world for a short span of time. As it is a novel virus, its manifestations have been slowly revealed. Cutaneous manifestations of COVID-19 have gradually been reported from different regions of the world. However, their significance in diagnosis, as well as predicting prognosis, remains to be established. This review describes the cutaneous manifestations of COVID-19 patients from diverse regions with the aim of highlighting any important associations. A literature search was conducted using "PubMed" for original articles, case series, and case reports using the search terms "cutaneous manifestations" and "skin manifestations" in combination with "COVID-19" published up to 31 May. Nine original research articles and 35 case series or case reports were identified, including 458 confirmed COVID-19 cases. The ratio of male to female patients was 0.94, and the patients' age ranged from 2 months to 84 years. In 10% of cases, skin lesions appeared before systemic manifestations. The most common cutaneous manifestation was macular/maculo-papular rash (42.5%), followed by acute urticaria (17.9%), vesicular rash (15.3%), pseudo-chilblain or acral purpuric lesions (1...Continue Reading

References

Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 28, 2020·Journal of the American Academy of Dermatology·Beuy Joob, Viroj Wiwanitkit
Apr 14, 2020·Journal of the American Academy of Dermatology·Iviensan F ManaloRandy Jacobs
Apr 16, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·D HenryE Esteve
Apr 18, 2020·Clinical and Experimental Dermatology·A Alramthan, W Aldaraji
Apr 20, 2020·Journal of the American Academy of Dermatology·Angelo Valerio MarzanoPiergiacomo Calzavara-Pinton
Apr 22, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·M HedouM Masson Regnault
Apr 22, 2020·Pediatric Dermatology·Giovanni GenoveseAngelo V Marzano
Apr 25, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·C van DammeO Accaputo
Apr 25, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A TammaroJ Rello
May 3, 2020·International Journal of Dermatology·Giovanni PaolinoFederica Pasi
May 3, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·Amir Hooshang EhsaniZeinab Bigdelo
May 10, 2020·Clinical and Experimental Dermatology·D Fernandez-NietoM Fernandez-Guarino
May 10, 2020·Clinical and Experimental Dermatology·J Jimenez-CauheD Fernandez-Nieto
May 10, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·C GunawanA Widysanto
May 10, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·H JanahJ Elbenaye
May 10, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A G LocatelliP Sena
May 10, 2020·Pediatric Dermatology·David AndinaAntonio Torrelo
May 12, 2020·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Miriam Morey-OlivéVicenç García-Patos
May 15, 2020·Clinical and Experimental Dermatology·R Cepeda-ValdesJ Salas-Alanis
May 19, 2020·Clinical and Experimental Dermatology·A Saenz AguirreR Gonzalez-Perez
May 21, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·M F García-GilM Ara-Martín
May 23, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·C GuarneriG Nunnari
May 25, 2020·Dermatologic Therapy·Mohamed L ElsaieHesham A Nada
May 27, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·R BalestriC R Girardelli
May 29, 2020·Brain, Behavior, and Immunity·Piotr K KrajewskiJoanna Maj
May 31, 2020·Dermatologic Therapy·Olga Yu OlisovaLidiya M Shnakhova
Jun 2, 2020·Journal of the American Academy of Dermatology·Esther E FreemanUNKNOWN American Academy of Dermatology Ad Hoc Task Force on COVID-19

❮ Previous
Next ❯

Citations

Oct 26, 2021·Hämostaseologie·Andrea Gawaz, Emmanuella Guenova

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cleveland Clinic Journal of Medicine
Sarah Young, Anthony P Fernandez
Clinical and Experimental Dermatology
D AndinaESPD Group for the Skin Manifestations of COVID-19
Clinical and Experimental Dermatology
D AndinaESPD Group for the Skin Manifestations of COVID-19
© 2021 Meta ULC. All rights reserved