PMID: 16511799Mar 3, 2006Paper

Cutaneous melanophoroma in a green iguana (Iguana iguana)

Veterinary Clinical Pathology
Armando R Irizarry-RoviraJ A Ramos-Vara

Abstract

An adult, male, green iguana (Iguana iguana) of unknown age was presented with a history of an enlarging, dark, skin mass in the right axillary region. The mass was excised because neoplasia was suspected. Impression smears of the cut surface of the mass were prepared for cytologic examination, and the mass was fixed for histologic examination. The impression smears contained numerous, discrete, pigmented, neoplastic cells consistent with melanin-producing neoplastic chromatophores. Histologic findings were consistent with a cutaneous melanophoroma. By transmission electron microscopy, the intracytoplasmic pigment granules corresponded to numerous melanosomes and lower numbers of premelanosomes. Tissue sections of the tumor were immunoreactive for Melan A antigen and were negative for S-100 antigen. The cytologic, histologic, electron microscopic, and immunohistochemical findings of the neoplasm were consistent with those of melanophoroma, an uncommon neoplasm of reptiles. The present report augments the limited body of knowledge on cytomorphologic and immunohistochemical characteristics of pigmented neoplasms in reptiles.

Citations

Sep 7, 2007·Veterinary Clinical Pathology·Armando R Irizarry-RoviraJosé A Ramos-Vara
Nov 19, 2011·Veterinary Clinical Pathology·Melinda S CamusAlvin C Camus
Mar 28, 2012·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Catherine A HadfieldRichard J Montali
Jun 29, 2013·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Elizabeth Morales SalinasSerafin J López Garrido
Aug 26, 2011·Journal of Comparative Pathology·K O HeckersM Pees
Jan 3, 2007·The Veterinary Clinics of North America. Exotic Animal Practice·Allan P Pessier
Sep 10, 2015·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Simone de BrotMaja Ruetten
Mar 16, 2012·The Veterinary Journal·Tom HellebuyckAn Martel
Jul 23, 2019·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Wesley C SiniardEsteban Soto

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